Literature DB >> 16402114

G-protein-coupled receptors: past, present and future.

Stephen J Hill1.   

Abstract

The G-protein-coupled receptor (GPCR) family represents the largest and most versatile group of cell surface receptors. Drugs active at these receptors have therapeutic actions across a wide range of human diseases ranging from allergic rhinitis to pain, hypertension and schizophrenia. This review provides a brief historical overview of the properties and signalling characteristics of this important family of receptors.

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Year:  2006        PMID： 16402114      PMCID： PMC1760739          DOI： 10.1038/sj.bjp.0706455

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  71 in total

Review 1.  G protein-coupled-receptor cross-talk: the fine-tuning of multiple receptor-signalling pathways.

Authors:  L A Selbie; S J Hill
Journal:  Trends Pharmacol Sci       Date:  1998-03       Impact factor: 14.819

Review 2.  Endocytosis and recycling of G protein-coupled receptors.

Authors:  J A Koenig; J M Edwardson
Journal:  Trends Pharmacol Sci       Date:  1997-08       Impact factor: 14.819

3.  Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin.

Authors:  R A Dixon; B K Kobilka; D J Strader; J L Benovic; H G Dohlman; T Frielle; M A Bolanowski; C D Bennett; E Rands; R E Diehl; R A Mumford; E E Slater; I S Sigal; M G Caron; R J Lefkowitz; C D Strader
Journal:  Nature       Date:  1986 May 1-7       Impact factor: 49.962

4.  The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange.

Authors:  R A Hall; R T Premont; C W Chow; J T Blitzer; J A Pitcher; A Claing; R H Stoffel; L S Barak; S Shenolikar; E J Weinman; S Grinstein; R J Lefkowitz
Journal:  Nature       Date:  1998-04-09       Impact factor: 49.962

5.  Guanosine 5'-(beta, gamma-imido)triphosphate inhibition of forskolin-activated adenylate cyclase is mediated by the putative inhibitory guanine nucleotide regulatory protein.

Authors:  K B Seamon; J W Daly
Journal:  J Biol Chem       Date:  1982-10-10       Impact factor: 5.157

6.  A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Authors:  G Grynkiewicz; M Poenie; R Y Tsien
Journal:  J Biol Chem       Date:  1985-03-25       Impact factor: 5.157

7.  Affinities of histamine H1-antagonists in guinea pig brain: similarity of values determined from [3H]mepyramine binding and from inhibition of a functional response.

Authors:  S J Hill; P Daum; J M Young
Journal:  J Neurochem       Date:  1981-11       Impact factor: 5.372

8.  Inositol phospholipid hydrolysis in rat cerebral cortical slices: I. Receptor characterisation.

Authors:  E Brown; D A Kendall; S R Nahorski
Journal:  J Neurochem       Date:  1984-05       Impact factor: 5.372

9.  Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands.

Authors:  M J Berridge; C P Downes; M R Hanley
Journal:  Biochem J       Date:  1982-09-15       Impact factor: 3.857

10.  The ternary complex model. Its properties and application to ligand interactions with the D2-dopamine receptor of the anterior pituitary gland.

Authors:  K A Wreggett; A De Léan
Journal:  Mol Pharmacol       Date:  1984-09       Impact factor: 4.436
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  53 in total

1.  V2 vasopressin receptor (V2R) mutations in partial nephrogenic diabetes insipidus highlight protean agonism of V2R antagonists.

Authors:  Kazuhiro Takahashi; Noriko Makita; Katsunori Manaka; Masataka Hisano; Yuko Akioka; Kenichiro Miura; Noriyuki Takubo; Atsuko Iida; Norishi Ueda; Makiko Hashimoto; Toshiro Fujita; Takashi Igarashi; Takashi Sekine; Taroh Iiri
Journal:  J Biol Chem       Date:  2011-12-05       Impact factor: 5.157

Review 2.  Allostery at G protein-coupled receptor homo- and heteromers: uncharted pharmacological landscapes.

Authors:  Nicola J Smith; Graeme Milligan
Journal:  Pharmacol Rev       Date:  2010-12       Impact factor: 25.468

3.  Receptor heterodimerization: a new level of cross-talk.

Authors:  Peter J Barnes
Journal:  J Clin Invest       Date:  2006-05       Impact factor: 14.808

Review 4.  Trace amine-associated receptors and their ligands.

Authors:  R Zucchi; G Chiellini; T S Scanlan; D K Grandy
Journal:  Br J Pharmacol       Date:  2006-11-06       Impact factor: 8.739

Review 5.  A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization.

Authors:  G Milligan
Journal:  Br J Pharmacol       Date:  2007-10-29       Impact factor: 8.739

6.  Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies.

Authors:  Achla Gupta; Raphael Rozenfeld; Ivone Gomes; Kirsten M Raehal; Fabien M Décaillot; Laura M Bohn; Lakshmi A Devi
Journal:  J Biol Chem       Date:  2008-02-06       Impact factor: 5.157

7.  Discovery and validation of novel peptide agonists for G-protein-coupled receptors.

Authors:  Ronen Shemesh; Amir Toporik; Zurit Levine; Iris Hecht; Galit Rotman; Assaf Wool; Dvir Dahary; Eyal Gofer; Yossef Kliger; Michal Ayalon Soffer; Avi Rosenberg; Dani Eshel; Yossi Cohen
Journal:  J Biol Chem       Date:  2008-10-09       Impact factor: 5.157

8.  Heterologous, PKC-Mediated Desensitization of Human Histamine H3 Receptors Expressed in CHO-K1 Cells.

Authors:  Wilber Montejo-López; Nayeli Rivera-Ramírez; Juan Escamilla-Sánchez; Ubaldo García-Hernández; José-Antonio Arias-Montaño
Journal:  Neurochem Res       Date:  2016-06-27       Impact factor: 3.996

9.  Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway.

Authors:  Huiping Song; Jian Luo; Weijia Luo; Jinsheng Weng; Zhiqiang Wang; Baoxing Li; Dali Li; Mingyao Liu
Journal:  J Biol Chem       Date:  2008-10-27       Impact factor: 5.157

10.  Epigenetic inactivation of galanin and GALR1/2 is associated with early recurrence in head and neck cancer.

Authors:  Kiyoshi Misawa; Yuki Misawa; Takeharu Kanazawa; Daiki Mochizuki; Atsushi Imai; Shiori Endo; Thomas E Carey; Hiroyuki Mineta
Journal:  Clin Exp Metastasis       Date:  2015-11-16       Impact factor: 5.150
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