Literature DB >> 16402045

Sphingosine-1-phosphate and sphingosylphosphorylcholine: two of a kind?

Astrid E Alewijnse1, Martin C Michel.   

Abstract

Sphingosine-1-phosphate and sphingosylphosphorylcholine are structurally related signalling molecules. Although they share some biological effects, it is debated whether this involves the same receptors. In this issue, Mathieson and Nixon report that these two lipids activate the same transcription factor but do so via distinct signalling pathways. Against this background, we discuss some of the potential pitfalls in studies comparing the effects of the two sphingolipids.

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Year:  2006        PMID： 16402045      PMCID： PMC1616987          DOI： 10.1038/sj.bjp.0706602

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  12 in total

1.  Sphingosylphosphorylcholine induces endothelial cell migration and morphogenesis.

Authors:  G Boguslawski; D Lyons; K A Harvey; A T Kovala; D English
Journal:  Biochem Biophys Res Commun       Date:  2000-06-07       Impact factor: 3.575

Review 2.  Proton-sensing and lysolipid-sensitive G-protein-coupled receptors: a novel type of multi-functional receptors.

Authors:  Hideaki Tomura; Chihiro Mogi; Koichi Sato; Fumikazu Okajima
Journal:  Cell Signal       Date:  2005-12       Impact factor: 4.315

3.  A novel membrane receptor with high affinity for lysosphingomyelin and sphingosine 1-phosphate in atrial myocytes.

Authors:  M Bünemann; K Liliom; B K Brandts; L Pott; J L Tseng; D M Desiderio; G Sun; D Miller; G Tigyi
Journal:  EMBO J       Date:  1996-10-15       Impact factor: 11.598

Review 4.  Cardiovascular effects of sphingosine-1-phosphate and other sphingomyelin metabolites.

Authors:  Astrid E Alewijnse; Stephan L M Peters; Martin C Michel
Journal:  Br J Pharmacol       Date:  2004-10-25       Impact factor: 8.739

5.  Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4.

Authors:  K Zhu; L M Baudhuin; G Hong; F S Williams; K L Cristina; J H Kabarowski; O N Witte; Y Xu
Journal:  J Biol Chem       Date:  2001-09-04       Impact factor: 5.157

6.  Sphingolipids differentially regulate mitogen-activated protein kinases and intracellular Ca2+ in vascular smooth muscle: effects on CREB activation.

Authors:  Fiona A Mathieson; Graeme F Nixon
Journal:  Br J Pharmacol       Date:  2006-02       Impact factor: 8.739

7.  A distinct G(i) protein-coupled receptor for sphingosylphosphorylcholine in human leukemia HL-60 cells and human neutrophils.

Authors:  C J Van Koppen; D Meyer Zu Heringdorf; C Zhang; K T Laser; K H Jakobs
Journal:  Mol Pharmacol       Date:  1996-06       Impact factor: 4.436

Review 8.  Discovery of new G protein-coupled receptors for lipid mediators.

Authors:  Dong-Soon Im
Journal:  J Lipid Res       Date:  2003-12-01       Impact factor: 5.922

Review 9.  Sphingosylphosphorylcholine and lysophosphatidylcholine: G protein-coupled receptors and receptor-mediated signal transduction.

Authors:  Yan Xu
Journal:  Biochim Biophys Acta       Date:  2002-05-23

Review 10.  Sphingosylphosphorylcholine-biological functions and mechanisms of action.

Authors:  Dagmar Meyer zu Heringdorf; Herbert M Himmel; Karl H Jakobs
Journal:  Biochim Biophys Acta       Date:  2002-05-23
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  4 in total

1.  A new mechanism for photo- and radiation-induced decomposition of sphingolipids.

Authors:  Alexandra G Lisovskaya; Oleg I Shadyro; Irina P Edimecheva
Journal:  Lipids       Date:  2010-12-08       Impact factor: 1.880

2.  Sphingosylphosphorylcholine activates dendritic cells, stimulating the production of interleukin-12.

Authors:  Ana Ceballos; Juan Sabatté; Karen Nahmod; Diego Martínez; Gabriela Salamone; Mónica Vermeulen; Julián Maggini; Horacio Salomón; Jorge Geffner
Journal:  Immunology       Date:  2007-03-20       Impact factor: 7.397

Review 3.  Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine.

Authors:  Denise G Hemmings
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2006-04       Impact factor: 3.000

4.  Indomethacin differentiates the renal effects of sphingosine-1-phosphate and sphingosylphosphorylcholine.

Authors:  Claudia Czyborra; Angela Bischoff; Martin C Michel
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2006-03-07       Impact factor: 3.000
  4 in total

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