| Literature DB >> 16401856 |
S Kuwabara1, S Misawa, K Kanai, Y Kikkawa, M Nishimura, C Nakaseko, R K Cho, T Hattori.
Abstract
Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome is a rare multisystem disorder. Overproduction of vascular endothelial growth factor (VEGF) by plasmocytoma could be responsible for the symptoms. The authors treated four patients with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. Within 6 months, symptoms associated with rapid normalization of serum VEGF levels improved.Entities:
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Year: 2006 PMID: 16401856 DOI: 10.1212/01.wnl.0000188757.38495.23
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910