Literature DB >> 16401316

The perils of procrastination: effects of early vs. delayed detection and treatment of incipient Charcot fracture.

E Chantelau1.   

Abstract

BACKGROUND: At the onset of acute diabetic Charcot foot, therapeutic intervention may be delayed because plain X-rays may not show fractures. AIM OF THE STUDY: To assess the clinical course of acute Charcot foot in 24 patients without evidence of definite fractures on the first X-ray after onset of symptoms, who were referred to the foot clinic for diagnosis and treatment either early or delayed, i.e. before or after definite fractures were detectable on repeat X-rays. PATIENTS AND METHODS: Eleven patients were referred early (incipient Charcot foot, case group), and 13 patients were referred delayed (overt Charcot foot, control group). In the foot clinic, both groups were immediately treated with off-loading and total contact casting. After the healing process of the Charcot foot was complete, the extent of fractures and subsequent deformities were evaluated.
RESULTS: Based on X-rays at the onset of symptoms, in 19 of the 24 patients the condition had been misdiagnosed prior to referral (in 11 patients as sprain injury). Additional imaging techniques (MRI, CT scan or bone scintigraphy) had been performed in 10 patients prior to referral. While these techniques had been used more frequently in the cases vs. the controls (P=0.012), misdiagnosis was less frequent in the cases vs. the controls (P=0.013). Only one out of 11 case patients developed extended foot fractures and severe deformity, vs. 12 out of 13 control patients (P<0.001).
CONCLUSION: Early detection of incipient Charcot foot is facilitated by imaging techniques other than plain X-rays. Immediate off-loading of incipient Charcot foot appears to minimize fractures and incapacitating deformities.

Entities:  

Mesh:

Year:  2005        PMID: 16401316     DOI: 10.1111/j.1464-5491.2005.01677.x

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  36 in total

1.  Role of dynamic MRI in the follow-up of acute Charcot foot in patients with diabetes mellitus.

Authors:  Virna Zampa; Irene Bargellini; Loredana Rizzo; Francesca Turini; Simona Ortori; Alberto Piaggesi; Carlo Bartolozzi
Journal:  Skeletal Radiol       Date:  2011-01-28       Impact factor: 2.199

2.  Proton magnetic resonance spectroscopy in the evaluation of patients with acute Charcot neuro-osteoarthropathy.

Authors:  Francesca Bolacchi; Luigi Uccioli; Salvatore Masala; Laura Giurato; Valeria Ruotolo; Marco Meloni; Eleonora Baffari; Elenia Cinelli; Marcello Cadioli; Ettore Squillaci; Giovanni Simonetti; Alberto Bergamini
Journal:  Eur Radiol       Date:  2013-06-11       Impact factor: 5.315

Review 3.  Updates on Diabetic Foot and Charcot Osteopathic Arthropathy.

Authors:  Brian M Schmidt; Crystal M Holmes
Journal:  Curr Diab Rep       Date:  2018-08-15       Impact factor: 4.810

4.  Pedal bone density, strength, orientation, and plantar loads preceding incipient metatarsal fracture after charcot neuroarthropathy: 2 case reports.

Authors:  David J Gutekunst; David R Sinacore
Journal:  J Orthop Sports Phys Ther       Date:  2013-09-09       Impact factor: 4.751

Review 5.  Special Considerations in the Management of Diabetic Ankle Fractures.

Authors:  Jeffrey M Manway; Cody D Blazek; Patrick R Burns
Journal:  Curr Rev Musculoskelet Med       Date:  2018-09

Review 6.  Lower limb complications of diabetes mellitus: a comprehensive review with clinicopathological insights from a dedicated high-risk diabetic foot multidisciplinary team.

Authors:  P Naidoo; V J Liu; M Mautone; S Bergin
Journal:  Br J Radiol       Date:  2015-06-25       Impact factor: 3.039

7.  Charcot osteoarthropathy in diabetes: A brief review with an emphasis on clinical practice.

Authors:  Evanthia Gouveri; Nikolaos Papanas
Journal:  World J Diabetes       Date:  2011-05-15

Review 8.  [Charcot foot. Current situation and outlook].

Authors:  T Mittlmeier; K Klaue; P Haar; M Beck
Journal:  Unfallchirurg       Date:  2008-04       Impact factor: 1.000

9.  Impact of Charcot neuroarthropathy on metatarsal bone mineral density and geometric strength indices.

Authors:  David J Gutekunst; Kirk E Smith; Paul K Commean; Kathryn L Bohnert; Fred W Prior; David R Sinacore
Journal:  Bone       Date:  2012-10-29       Impact factor: 4.398

10.  Role of quantitative bone scanning in the assessment of bone turnover in patients with Charcot foot.

Authors:  Robert Bem; Alexandra Jirkovská; Michal Dubsky; Vladimira Fejfarová; Marie Buncová; Jelena Skibová; Edward B Jude
Journal:  Diabetes Care       Date:  2009-11-23       Impact factor: 19.112

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