Literature DB >> 16401223

Preliminary report: Correct diagnosis of sex in fetal cells isolated from cervical mucus during early pregnancy.

Debbie Mantzaris1, David Cram, Christine Healy, Donna Howlett, Gab Kovacs.   

Abstract

The aim of this study was to determine the accuracy of sexing fetal cells isolated from cervical mucus. Immunopositive cells identified using a fetal-specific antibody were isolated and subjected to genetic analysis. Fetal sex was predicted in all 22 samples, as confirmed by analysis of the corresponding placental tissue. This study validates the accuracy of our test for sex diagnosis and confirms the ability to effectively recover and analyse fetal cells from the cervical mucus during early pregnancy.

Mesh:

Year:  2005        PMID: 16401223     DOI: 10.1111/j.1479-828X.2005.00492.x

Source DB:  PubMed          Journal:  Aust N Z J Obstet Gynaecol        ISSN: 0004-8666            Impact factor:   2.100


  3 in total

1.  Fluorescent in situ hybridization for sex chromosome determination before and after fertilization in mice.

Authors:  J J Whyte; R M Roberts; C S Rosenfeld
Journal:  Theriogenology       Date:  2007-01-09       Impact factor: 2.740

2.  Prenatal screening methods for aneuploidies.

Authors:  Madhusudan Dey; Sumedha Sharma; Sumita Aggarwal
Journal:  N Am J Med Sci       Date:  2013-03

Review 3.  Trophoblast retrieval and isolation from the cervix: origins of cervical trophoblasts and their potential value for risk assessment of ongoing pregnancies.

Authors:  Gerit Moser; Sascha Drewlo; Berthold Huppertz; D Randall Armant
Journal:  Hum Reprod Update       Date:  2018-07-01       Impact factor: 15.610

  3 in total

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