Literature DB >> 16399371

Epoxide hydrolases: structure, function, mechanism, and assay.

Michael Arand1, Annette Cronin, Magdalena Adamska, Franz Oesch.   

Abstract

Epoxide hydrolases are a class of enzymes important in the detoxification of genotoxic compounds, as well as in the control of physiological signaling molecules. This chapter gives an overview on the function, structure, and enzymatic mechanism of structurally characterized epoxide hydrolases and describes selected assays for the quantification of epoxide hydrolase activity.

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Year:  2005        PMID： 16399371     DOI： 10.1016/S0076-6879(05)00032-7

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  29 in total

1.  Pseudomonas aeruginosa Cif defines a distinct class of α/β epoxide hydrolases utilizing a His/Tyr ring-opening pair.

Authors:  Christopher D Bahl; Dean R Madden
Journal:  Protein Pept Lett       Date:  2012-02       Impact factor: 1.890

2.  Development of a high-throughput screen for soluble epoxide hydrolase inhibition.

Authors:  Nicola M Wolf; Christophe Morisseau; Paul D Jones; Bertold Hock; Bruce D Hammock
Journal:  Anal Biochem       Date:  2006-05-11       Impact factor: 3.365

3.  Investigation of the binding mode of 1, 3, 4-oxadiazole derivatives as amide-based inhibitors for soluble epoxide hydrolase (sEH) by molecular docking and MM-GBSA.

Authors:  Leila Karami; Ali Akbar Saboury; Elham Rezaee; Sayyed Abbas Tabatabai
Journal:  Eur Biophys J       Date:  2016-12-07       Impact factor: 1.733

4.  Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis.

Authors:  Alena Stsiapanava; Bengt Samuelsson; Jesper Z Haeggström
Journal:  Proc Natl Acad Sci U S A       Date:  2017-08-21       Impact factor: 11.205

Review 5.  Mechanisms of tumor cell resistance to the current targeted-therapy agents.

Authors:  Gholamreza Khamisipour; Farhad Jadidi-Niaragh; Abdolreza Sotoodeh Jahromi; Keivan Zandi; Mohammad Hojjat-Farsangi
Journal:  Tumour Biol       Date:  2016-05-07

6.  Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor.

Authors:  Christopher D Bahl; Christophe Morisseau; Jennifer M Bomberger; Bruce A Stanton; Bruce D Hammock; George A O'Toole; Dean R Madden
Journal:  J Bacteriol       Date:  2010-01-29       Impact factor: 3.490

7.  Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice.

Authors:  Marc Revermann; Manuel Schloss; Eduardo Barbosa-Sicard; Anja Mieth; Stefan Liebner; Christophe Morisseau; Gerd Geisslinger; Ralph T Schermuly; Ingrid Fleming; Bruce D Hammock; Ralf P Brandes
Journal:  Arterioscler Thromb Vasc Biol       Date:  2010-03-11       Impact factor: 8.311

8.  Inhibition of the soluble epoxide hydrolase promotes albuminuria in mice with progressive renal disease.

Authors:  Oliver Jung; Felix Jansen; Anja Mieth; Eduardo Barbosa-Sicard; Rainer U Pliquett; Andrea Babelova; Christophe Morisseau; Sung H Hwang; Cindy Tsai; Bruce D Hammock; Liliana Schaefer; Gerd Geisslinger; Kerstin Amann; Ralf P Brandes
Journal:  PLoS One       Date:  2010-08-04       Impact factor: 3.240

9.  Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis.

Authors:  Christopher P Thomas; William E Boeglin; Yoel Garcia-Diaz; Valerie B O'Donnell; Alan R Brash
Journal:  Chem Phys Lipids       Date:  2013-01-23       Impact factor: 3.329

10.  Förster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase.

Authors:  Kin Sing Stephen Lee; Christophe Morisseau; Jun Yang; Peng Wang; Sung Hee Hwang; Bruce D Hammock
Journal:  Anal Biochem       Date:  2012-12-05       Impact factor: 3.365
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