Literature DB >> 163973

Ethidium bromide inhibits appearance of closed circular viral DNA and integration of virus-specific DNA in duck cells infected by avian sarcoma virus.

R V Guntaka, B W Mahy, J M Bishop, H E Varmus.   

Abstract

The DNA of avian sarcoma virus assumes a closed circular configuration before integration into the host cell chromosomal DNA. Ethidium bromide reduces the formation of superhelical viral DNA and concurrently blocks integration of the viral genome. Inhibition of integration of viral DNA results in the inhibition of virus replication.

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Year:  1975        PMID： 163973     DOI： 10.1038/253507a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  44 in total

1.  Production of avian oncoviral subgroups after multiple infection.

Authors:  A T Khoury; H Hanafusa; C A Namy
Journal:  J Virol       Date:  1979-03       Impact factor: 5.103

2.  Monomer and multimer covalently closed circular forms of Rous sarcoma virus DNA.

Authors:  G Goubin; M Hill
Journal:  J Virol       Date:  1979-02       Impact factor: 5.103

3.  Analysis of unintegrated avian RNA tumor virus double-stranded DNA intermediates.

Authors:  T W Hsu; J L Sabran; G E Mark; R V Guntaka; J M Taylor
Journal:  J Virol       Date:  1978-12       Impact factor: 5.103

4.  Infectious viral DNA of murine leukemia virus.

Authors:  D Smotkin; A M Gianni; S Rozenblatt; R A Weinberg
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

5.  Site on the RNA of an avian sarcoma virus at which primer is bound.

Authors:  J M Taylor; R Illmensee
Journal:  J Virol       Date:  1975-09       Impact factor: 5.103

6.  Use of alkaline sucrose gradients in a zonal rotor to detect integrated and unintegrated avian sarcoma virus-specific DNA in cells.

Authors:  H E Varmus; S Heasley; J Linn; K Wheeler
Journal:  J Virol       Date:  1976-05       Impact factor: 5.103

7.  Murine mammary tumor virus: characterization of infection of nonmurine cells.

Authors:  A B Vaidya; E Y Lasfargues; G Heubel; J C Lasfargues; D H Moore
Journal:  J Virol       Date:  1976-06       Impact factor: 5.103

8.  Synethesis and integration of viral DNA in chicken cells at different time after infection with various multiplicities of avian oncornavirus.

Authors:  A T Khoury; H Hanafusa
Journal:  J Virol       Date:  1976-05       Impact factor: 5.103

9.  Effect of oncogenic virus on muscle differentiation.

Authors:  H Holtzer; J Biehl; G Yeoh; R Meganathan; A Kaji
Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205

10.  Introduction of interrupted secondary structure in supercoiled DNA as a function of superhelix density: consideration of hairpin structures in superhelical DNA.

Authors:  M Woodworth-Gutai; J Lebowitz
Journal:  J Virol       Date:  1976-04       Impact factor: 5.103
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