Literature DB >> 16396321

[Determination of BCR/ABL translocation in radiation-associated acute myeloid leukemia patients by fluorescence in situ hybridization].

S V Klymenko, Zh A Misharina, I V Abramenko, N I Bilous, V H Bebeshko.   

Abstract

We report the results of BCR/ABL translocation analysis on interphase leukemic cells of 33 acute myeloid leukemia (AML) patients by fluorescence in situ hybridization. Of these, there were 13 persons exposed to ionizing radiation due to the Chernobyl accident with radiation-associated AML and 20 patients with spontaneous disease. BCR/ABL translocation which was detected in 4 and I case respectively may play an important role in radiation-induced leukemigenesis.

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Year:  2005        PMID： 16396321

Source DB:  PubMed          Journal:  Tsitol Genet        ISSN： 0564-3783


  2 in total

1.  RAD59 is required for efficient repair of simultaneous double-strand breaks resulting in translocations in Saccharomyces cerevisiae.

Authors:  Nicholas R Pannunzio; Glenn M Manthey; Adam M Bailis
Journal:  DNA Repair (Amst)       Date:  2008-03-25

2.  Msh2 blocks an alternative mechanism for non-homologous tail removal during single-strand annealing in Saccharomyces cerevisiae.

Authors:  Glenn M Manthey; Nilan Naik; Adam M Bailis
Journal:  PLoS One       Date:  2009-10-16       Impact factor: 3.240
  2 in total

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