Literature DB >> 16395833

Drotrecogin alfa (activated) in severe sepsis.

Steven P LaRosa.   

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Year:  2006        PMID: 16395833

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


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  8 in total

1.  An update on activated protein C (xigris) in the management of sepsis.

Authors:  Cesar Alaniz
Journal:  P T       Date:  2010-09

2.  How many patients with severe sepsis are needed to confirm the efficacy of drotrecogin alfa activated? A Bayesian design.

Authors:  Andre C Kalil; Junfeng Sun
Journal:  Intensive Care Med       Date:  2008-05-27       Impact factor: 17.440

Review 3.  Activated protein C in sepsis: the promise of nonanticoagulant activated protein C.

Authors:  Hartmut Weiler; Wolfram Ruf
Journal:  Curr Opin Hematol       Date:  2008-09       Impact factor: 3.284

4.  Medical guidelines and performance measures: the need to keep them free of industry influence.

Authors:  Peter Q Eichacker; Charles Natanson
Journal:  Mens Sana Monogr       Date:  2008-01

5.  Drotrecogin alfa (activated) should not be used in patients with severe sepsis and low risk for death.

Authors:  Sanjay Gupta; Eric B Milbrandt; Lakshmipathi Chelluri
Journal:  Crit Care       Date:  2006       Impact factor: 9.097

Review 6.  Drotrecogin alfa (activated): does current evidence support treatment for any patients with severe sepsis?

Authors:  Jan O Friedrich; Neill K J Adhikari; Maureen O Meade
Journal:  Crit Care       Date:  2006-06-02       Impact factor: 9.097

7.  Growing insights into the potential benefits and risks of activated protein C administration in sepsis: a review of preclinical and clinical studies.

Authors:  Laith Altaweel; Daniel Sweeney; Xizhong Cui; Amisha Barochia; Charles Natanson; Peter Q Eichacker
Journal:  Biologics       Date:  2009-09-15

8.  Why are clinicians not embracing the results from pivotal clinical trials in severe sepsis? A bayesian analysis.

Authors:  Andre C Kalil; Junfeng Sun
Journal:  PLoS One       Date:  2008-05-28       Impact factor: 3.240

  8 in total

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