| Literature DB >> 16395649 |
Haibo Li1, Changxin Zhou, Yunxue Pan, Xiaozhong Gao, Xiumei Wu, Hua Bai, Linfu Zhou, Zhi Chen, Shuili Zhang, Shuyun Shi, Jiali Luo, Juanhua Xu, Liurong Chen, Xiaoxiang Zheng, Yu Zhao.
Abstract
Nineteen compounds isolated from Ranunculus sieboldii and Ranunculus sceleratus were tested for inhibitory effects on hepatitis B virus (HBV) and Herpes simplex virus type-1 (HSV-1). The results showed that apigenin 4'- O- alpha-rhamnopyranoside, apigenin 7- O- beta-glucopyranosyl-4'- O- alpha-rhamnopyranoside, tricin 7- O- beta-glucopyranoside, tricin, and isoscopoletin possessed inhibitory activity against HBV replication. Protocatechuyl aldehyde exhibited an inhibiting activity on HSV-1 replication. It is therefore suggested that further investigations on these bioactive compounds might be needed to discover and develop new antiviral agents.Entities:
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Year: 2005 PMID: 16395649 DOI: 10.1055/s-2005-873169
Source DB: PubMed Journal: Planta Med ISSN: 0032-0943 Impact factor: 3.352