Literature DB >> 16395323

Phosphodiesterase 11: a brief review of structure, expression and function.

A Makhlouf1, A Kshirsagar, C Niederberger.   

Abstract

Phosphodiesterase 11 (PDE11) is the latest isoform of the phosphodiesterase family to be identified. Interest in PDE11 has increased recently because tadalafil, an oral phosphodiesterase 5 inhibitor, cross reacts with PDE11. The function of PDE11 remains largely unknown, but growing evidence points to a possible role in male reproduction. The published literature on PDE11 structure, function and expression is reviewed.

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Year:  2006        PMID： 16395323     DOI： 10.1038/sj.ijir.3901441

Source DB:  PubMed          Journal:  Int J Impot Res        ISSN： 0955-9930            Impact factor:   2.896


  10 in total

Review 1.  Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments.

Authors:  Thérèse Keravis; Claire Lugnier
Journal:  Br J Pharmacol       Date:  2012-03       Impact factor: 8.739

Review 2.  Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatment.

Authors:  Isaac Levy; Anelia Horvath; Monalisa Azevedo; Rodrigo Bertollo de Alexandre; Constantine A Stratakis
Journal:  Curr Opin Pharmacol       Date:  2011-10-31       Impact factor: 5.547

3.  Inhibitors of phosphodiesterase 5 (PDE 5) inhibit the nerve-induced release of nitric oxide from the rabbit corpus cavernosum.

Authors:  K Hallén; N P Wiklund; L E Gustafsson
Journal:  Br J Pharmacol       Date:  2006-12-18       Impact factor: 8.739

Review 4.  A Role for Phosphodiesterase 11A (PDE11A) in the Formation of Social Memories and the Stabilization of Mood.

Authors:  Michy P Kelly
Journal:  Adv Neurobiol       Date:  2017

Review 5.  Adverse effects of common medications on male fertility.

Authors:  Mary K Samplaski; Ajay K Nangia
Journal:  Nat Rev Urol       Date:  2015-06-23       Impact factor: 14.432

Review 6.  Phosphodiesterase isoforms and cAMP compartments in the development of new therapies for obstructive pulmonary diseases.

Authors:  Martina Schmidt; Isabella Cattani-Cavalieri; Francisco J Nuñez; Rennolds S Ostrom
Journal:  Curr Opin Pharmacol       Date:  2020-07-01       Impact factor: 5.547

7.  Cyclic AMP, protein kinase A, and phosphodiesterases: proceedings of an international workshop.

Authors:  C A Stratakis
Journal:  Horm Metab Res       Date:  2012-09-05       Impact factor: 2.936

8.  Investigation of PDE5/PDE6 and PDE5/PDE11 selective potent tadalafil-like PDE5 inhibitors using combination of molecular modeling approaches, molecular fingerprint-based virtual screening protocols and structure-based pharmacophore development.

Authors:  Gülru Kayık; Nurcan Ş Tüzün; Serdar Durdagi
Journal:  J Enzyme Inhib Med Chem       Date:  2017-12       Impact factor: 5.051

9.  Investigating the effect of sildenafil on improving lung function and quality of life in the patients with severe asthma.

Authors:  Hamid Borsi; Hanieh Raji; Maryam Haddadzadeh Shoushtari; Heshmatollah Tavakol; Mohammad Hossein Haghighizadeh; Mehrdad Dargahi Mal-Amir
Journal:  J Family Med Prim Care       Date:  2019-07

10.  Functional characteristics and research trends of PDE11A in human diseases (Review).

Authors:  Gyeyeong Kong; Hyunji Lee; Thuy-Trang T Vo; Uijin Juang; So Hee Kwon; Jisoo Park; Jongsun Park; Seon-Hwan Kim
Journal:  Mol Med Rep       Date:  2022-08-05       Impact factor: 3.423
  10 in total

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