BACKGROUND: In the dermatology field, variable-pulse 595 nm pulsed dye lasers (PDLs) are now being widely used to treat vascular skin lesions. However, there is little information available on variable-pulse 595 nm PDL treatment of dark-skinned patients. OBJECTIVE: The objective of this study was to evaluate the outcome of variable-pulse 595 nm PDL treatment on Korean patients. METHOD: Two hundred thirty-nine patients (Fitzpatrick skin phototypes III to V) with vascular skin lesions, such as nevus flammeus, telangiectasia, or hemangioma, were included in this study. All patients were treated with a variable-pulse 595 nm PDL, and the outcomes were assessed by comparing preoperative and postoperative photographs. RESULTS: The average number of treatments per patient was 4.29, and 51.9% of patients showed a good (51-75% clearance) to excellent (76-100% clearance) response. For nevus flammeus, 48.0% of the patients achieved good to excellent results. The gender and age of the patients did not influence the clinical response; however, lesions of the head and neck were found to respond more favorably to treatment. For telangiectasia, 78.0% of patients showed good to excellent results, and, again, the gender and age of the patients did not alter the treatment outcome. For hemangioma, the male to female ratio of patients was 1.0:3.1 and 54.1% of the patients achieved a good to excellent response. Superficial hemangioma showed a better clinical response than deep hemangioma, and the lesions of younger patients responded more favorably than those of older patients. CONCLUSION: The variable-pulse 595 nm PDL was found to be effective for treating several vascular skin lesions in dark-skinned patients. However, there were differences in treatment outcome owing to disease, age, and the location of the lesions.
BACKGROUND: In the dermatology field, variable-pulse 595 nm pulsed dye lasers (PDLs) are now being widely used to treat vascular skin lesions. However, there is little information available on variable-pulse 595 nm PDL treatment of dark-skinned patients. OBJECTIVE: The objective of this study was to evaluate the outcome of variable-pulse 595 nm PDL treatment on Korean patients. METHOD: Two hundred thirty-nine patients (Fitzpatrick skin phototypes III to V) with vascular skin lesions, such as nevus flammeus, telangiectasia, or hemangioma, were included in this study. All patients were treated with a variable-pulse 595 nm PDL, and the outcomes were assessed by comparing preoperative and postoperative photographs. RESULTS: The average number of treatments per patient was 4.29, and 51.9% of patients showed a good (51-75% clearance) to excellent (76-100% clearance) response. For nevus flammeus, 48.0% of the patients achieved good to excellent results. The gender and age of the patients did not influence the clinical response; however, lesions of the head and neck were found to respond more favorably to treatment. For telangiectasia, 78.0% of patients showed good to excellent results, and, again, the gender and age of the patients did not alter the treatment outcome. For hemangioma, the male to female ratio of patients was 1.0:3.1 and 54.1% of the patients achieved a good to excellent response. Superficial hemangioma showed a better clinical response than deep hemangioma, and the lesions of younger patients responded more favorably than those of older patients. CONCLUSION: The variable-pulse 595 nm PDL was found to be effective for treating several vascular skin lesions in dark-skinned patients. However, there were differences in treatment outcome owing to disease, age, and the location of the lesions.
Authors: Jennifer K Chen; Pedram Ghasri; Guillermo Aguilar; Anne Margreet van Drooge; Albert Wolkerstorfer; Kristen M Kelly; Michal Heger Journal: J Am Acad Dermatol Date: 2012-02-03 Impact factor: 11.527
Authors: Guillermo Aguilar; Bernard Choi; Mans Broekgaarden; Owen Yang; Bruce Yang; Pedram Ghasri; Jennifer K Chen; Rick Bezemer; J Stuart Nelson; Anne Margreet van Drooge; Albert Wolkerstorfer; Kristen M Kelly; Michal Heger Journal: Ann Biomed Eng Date: 2011-10-21 Impact factor: 3.934
Authors: M Ingmar van Raath; Jojanneke E van Amesfoort; Martin Hermann; Yasin Ince; Maurice J Zwart; Agustina V Echague; Yan Chen; Baoyue Ding; Xuan Huang; Gert Storm; Michal Heger Journal: J Clin Transl Res Date: 2019-05-01
Authors: Sara Sabeti; Karen L Ball; Craig Burkhart; Lawrence Eichenfield; Esteban Fernandez Faith; Ilona J Frieden; Roy Geronemus; Deepti Gupta; Andrew C Krakowski; Moise L Levy; Denise Metry; J Stuart Nelson; Megha M Tollefson; Kristen M Kelly Journal: JAMA Dermatol Date: 2021-01-01 Impact factor: 10.282