Literature DB >> 16393330

Agents causing occupational asthma in Finland in 1986-2002: cow epithelium bypassed by moulds from moisture-damaged buildings.

R Piipari1, H Keskinen.   

Abstract

BACKGROUND: Occupational asthma is an avoidable form of asthma. In Finland, the diagnosis of occupational asthma entitles substantial compensation to the employee. The diagnostics are based on symptoms, exposure assessment, allergologic investigations, follow-up of peak expiratory flow (PEF) at work and at home and, in many cases, specific challenge tests.
OBJECTIVE: To study the causative agents of occupational asthma in Finland.
METHODS: The causative agents and the numbers of new occupational asthma cases notified to the Finnish Register of Occupational Diseases (FROD) during 1986-2002 are reported.
RESULTS: The number of occupational asthma cases increased from 1986 until 1995, after which a downward trend, stabilizing during the last few years, has been observed. The majority of the cases (59%) in the beginning of the period (1986-1990) were associated with agriculture, but the percentage has fallen thereafter (42% of the cases in 1998-2002) along with the fall in the total number of cases. Since 1995, indoor moulds from water-damaged buildings have caused an increasing number of cases and have become the most important causative agents (0.5% cases, in 1986-1990 and 18% of the cases in 1998-2002). Chemicals have caused 10-30% of the cases, a decreasing number since 1990. The most important chemicals causing occupational asthma have been diisocyanates and welding fumes, followed by hairdressing chemicals and formaldehyde.
CONCLUSIONS: The number of occupational asthma cases in Finland reached its height in the mid-1990s. The decrease in the number of total cases is because of the decrease in agriculture-associated cases, reflecting the number of employees in agriculture-associated occupations, which has greatly decreased since Finland joined the EU in 1995. An epidemic of mould-induced asthma, affecting mostly white-collar employees working in moisture-damaged buildings, has taken place since 1995.

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Year:  2005        PMID: 16393330     DOI: 10.1111/j.1365-2222.2005.02386.x

Source DB:  PubMed          Journal:  Clin Exp Allergy        ISSN: 0954-7894            Impact factor:   5.018


  11 in total

1.  Asthma related to workplace dampness and impaired work ability.

Authors:  Kirsi Karvala; Henrik Nordman; Ritva Luukkonen; Jukka Uitti
Journal:  Int Arch Occup Environ Health       Date:  2012-12-04       Impact factor: 3.015

2.  Prolonged exposure to damp and moldy workplaces and new-onset asthma.

Authors:  Kirsi Karvala; Elina Toskala; Ritva Luukkonen; Jukka Uitti; Sanna Lappalainen; Henrik Nordman
Journal:  Int Arch Occup Environ Health       Date:  2011-07-19       Impact factor: 3.015

3.  New-onset adult asthma in relation to damp and moldy workplaces.

Authors:  Kirsi Karvala; Elina Toskala; Ritva Luukkonen; Sanna Lappalainen; Jukka Uitti; Henrik Nordman
Journal:  Int Arch Occup Environ Health       Date:  2010-02-03       Impact factor: 3.015

Review 4.  When to suspect occupational asthma.

Authors:  Catherine Lemière
Journal:  Can Respir J       Date:  2013 Nov-Dec       Impact factor: 2.409

5.  Bakery flour dust exposure causes non-allergic inflammation and enhances allergic airway inflammation in mice.

Authors:  P Marraccini; D M Brass; J W Hollingsworth; S Maruoka; S Garantziotis; D A Schwartz
Journal:  Clin Exp Allergy       Date:  2008-06-28       Impact factor: 5.018

6.  Bronchial asthma and COPD due to irritants in the workplace - an evidence-based approach.

Authors:  Xaver Baur; Prudence Bakehe; Henning Vellguth
Journal:  J Occup Med Toxicol       Date:  2012-09-26       Impact factor: 2.646

7.  Testing for cattle allergy: modified diagnostic cutoff levels improve sensitivity in symptomatic claw trimmers.

Authors:  Astrid Heutelbeck; Natalja Dik; Ernst Hallier; Torsten Zuberbier; Karl-Christian Bergmann
Journal:  Int Arch Occup Environ Health       Date:  2010-07-24       Impact factor: 3.015

8.  Occupational asthma: etiologies and risk factors.

Authors:  Olivier Vandenplas
Journal:  Allergy Asthma Immunol Res       Date:  2011-05-20       Impact factor: 5.764

9.  Assessment of public health impact of work-related asthma.

Authors:  Maritta S Jaakkola; Jouni J K Jaakkola
Journal:  BMC Med Res Methodol       Date:  2012-03-05       Impact factor: 4.615

10.  Fungal allergy in asthma-state of the art and research needs.

Authors:  David W Denning; Catherine Pashley; Domink Hartl; Andrew Wardlaw; Cendrine Godet; Stefano Del Giacco; Laurence Delhaes; Svetlana Sergejeva
Journal:  Clin Transl Allergy       Date:  2014-04-15       Impact factor: 5.871

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