Literature DB >> 1639242

Triflusal vs aspirin on the inhibition of human platelet and vascular cyclooxygenase.

J P de la Cruz1, J M Mata, F Sanchez de la Cuesta.   

Abstract

1. Triflusal is a salicylic derivative that inhibits platelet aggregation in human whole blood with a minimal inhibition of prostacyclin production. 2. Aspirin inhibits platelet aggregation at concentrations that reduce vascular prostacyclin production.

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Year:  1992        PMID： 1639242     DOI： 10.1016/0306-3623(92)90027-h

Source DB:  PubMed          Journal:  Gen Pharmacol        ISSN： 0306-3623


  7 in total

Review 1.  Triflusal: a review of its use in cerebral infarction and myocardial infarction, and as thromboprophylaxis in atrial fibrillation.

Authors:  David Murdoch; Greg L Plosker
Journal:  Drugs       Date:  2006       Impact factor: 9.546

2.  Effect of 4-trifluoromethyl derivatives of salicylate on nuclear factor kappaB-dependent transcription in human astrocytoma cells.

Authors:  M Hernández; A F de Arriba; M Merlos; L Fuentes; M S Crespo; M L Nieto
Journal:  Br J Pharmacol       Date:  2001-01       Impact factor: 8.739

3.  Triflusal : A Viewpoint by José P. De La Cruz.

Authors:  J P De La Cruz
Journal:  Drugs       Date:  1998-06       Impact factor: 9.546

4.  Protective effect of triflusal and its main metabolite HTB in an in vitro model of anoxia-reoxygenation in rat brain slices: comparison with acetylsalicylic and salicylic acids.

Authors:  J A González-Correa; M M Arrebola; I M Ureña; D Ruiz-Villafranca; J Muñoz-Marín; A Guerrero; F Sánchez de la Cuesta; J P De La Cruz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2004-12-16       Impact factor: 3.000

Review 5.  Triflusal.

Authors:  W McNeely; K L Goa
Journal:  Drugs       Date:  1998-06       Impact factor: 9.546

6.  Effects of triflusal and its main metabolite HTB on platelet interaction with subendothelium in healthy volunteers.

Authors:  J P De La Cruz; M A Villalobos; P J García; J M Smith-Agreda; F Sánchez de la Cuesta
Journal:  Eur J Clin Pharmacol       Date:  1995       Impact factor: 2.953

7.  Effect of Triflusal on Primary Vascular Dysregulation Compared with Aspirin: A Double-Blind, Randomized, Crossover Trial.

Authors:  Sanghoon Shin; Kwang-Joon Kim; In-Jeong Cho; Geu-Ru Hong; Yangsoo Jang; Namsik Chung; Young Min Rah; Hyuk-Jae Chang
Journal:  Yonsei Med J       Date:  2015-09       Impact factor: 2.759
  7 in total

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