Literature DB >> 16392084

Laboratory medicine in Africa: a barrier to effective health care.

Cathy A Petti1, Christopher R Polage, Thomas C Quinn, Allan R Ronald, Merle A Sande.   

Abstract

Providing health care in sub-Saharan Africa is a complex problem. Recent reports call for more resources to assist in the prevention and treatment of infectious diseases that affect this population, but policy makers, clinicians, and the public frequently fail to understand that diagnosis is essential to the prevention and treatment of disease. Access to reliable diagnostic testing is severely limited in this region, and misdiagnosis commonly occurs. Understandably, allocation of resources to diagnostic laboratory testing has not been a priority for resource-limited health care systems, but unreliable and inaccurate laboratory diagnostic testing leads to unnecessary expenditures in a region already plagued by resource shortages, promotes the perception that laboratory testing is unhelpful, and compromises patient care. We explore the barriers to implementing consistent testing within this region and illustrate the need for a more comprehensive approach to the diagnosis of infectious diseases, with an emphasis on making laboratory testing a higher priority.

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Year:  2005        PMID: 16392084     DOI: 10.1086/499363

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  307 in total

1.  Immunologic criteria are poor predictors of virologic outcome: implications for HIV treatment monitoring in resource-limited settings.

Authors:  Holly E Rawizza; Beth Chaplin; Seema T Meloni; Geoffrey Eisen; Tara Rao; Jean-Louis Sankalé; Abdoulaye Dieng-Sarr; Oche Agbaji; Daniel I Onwujekwe; Wadzani Gashau; Reuben Nkado; Ernest Ekong; Prosper Okonkwo; Robert L Murphy; Phyllis J Kanki
Journal:  Clin Infect Dis       Date:  2011-12       Impact factor: 9.079

2.  Promoting good clinical laboratory practices and laboratory accreditation to support clinical trials in sub-Saharan Africa.

Authors:  Merepen A Guindo; Joseph P Shott; Renion Saye; Moussa L Diakité; Sintry Sanogo; Moussa B Dembele; Sekouba Keita; Mary C Nagel; Ruth D Ellis; Joan A Aebig; Dapa A Diallo; Ogobara K Doumbo
Journal:  Am J Trop Med Hyg       Date:  2012-04       Impact factor: 2.345

3.  Aggregate evaluable organ dysfunction predicts in-hospital mortality from sepsis in Uganda.

Authors:  Richard Ssekitoleko; Relana Pinkerton; Rose Muhindo; Sanjay Bhagani; Christopher C Moore
Journal:  Am J Trop Med Hyg       Date:  2011-10       Impact factor: 2.345

4.  Concordance of programmatic and laboratory-based multidrug-resistant tuberculosis treatment outcomes in Peru.

Authors:  E R Alexy; L J Podewils; C D Mitnick; M C Becerra; K F Laserson; C Bonilla
Journal:  Int J Tuberc Lung Dis       Date:  2012       Impact factor: 2.373

5.  Assessing the performance of CareStart Malaria Pf/Pv Combo Test against thick blood film in the diagnosis of malaria in northwest Ethiopia.

Authors:  Tadesse Hailu; Tadesse Kebede
Journal:  Am J Trop Med Hyg       Date:  2014-03-31       Impact factor: 2.345

6.  Diurnal variation in trauma mortality in sub-Saharan Africa: A proxy for health care system maturity.

Authors:  Jared R Gallaher; Carlos Varela; Laura N Purcell; Rebecca Maine; Anthony Charles
Journal:  Injury       Date:  2019-11-09       Impact factor: 2.586

7.  Namibia's transition from whole blood-derived pooled platelets to single-donor apheresis platelet collections.

Authors:  John P Pitman; Sridhar V Basavaraju; Ray W Shiraishi; Robert Wilkinson; Bjorn von Finckenstein; David W Lowrance; Anthony A Marfin; Maarten Postma; Mary Mataranyika; Cees Th Smit Sibinga
Journal:  Transfusion       Date:  2015-02-27       Impact factor: 3.157

8.  Laboratory challenges conducting international clinical research in resource-limited settings.

Authors:  Joseph E Fitzgibbon; Carole L Wallis
Journal:  J Acquir Immune Defic Syndr       Date:  2014-01-01       Impact factor: 3.731

9.  Diagnosis of Schistosoma haematobium infection with a mobile phone-mounted Foldscope and a reversed-lens CellScope in Ghana.

Authors:  Richard K D Ephraim; Evans Duah; James S Cybulski; Manu Prakash; Michael V D'Ambrosio; Daniel A Fletcher; Jennifer Keiser; Jason R Andrews; Isaac I Bogoch
Journal:  Am J Trop Med Hyg       Date:  2015-04-27       Impact factor: 2.345

10.  Evaluation of Malaria Diagnoses Using a Handheld Light Microscope in a Community-Based Setting in Rural Côte d'Ivoire.

Authors:  Jean T Coulibaly; Mamadou Ouattara; Jennifer Keiser; Bassirou Bonfoh; Eliézer K N'Goran; Jason R Andrews; Isaac I Bogoch
Journal:  Am J Trop Med Hyg       Date:  2016-08-15       Impact factor: 2.345

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