Study focuses in on potential cause of antipsychotic-induced diabetes.

First-generation antipsychotic drugs, efficacious in reducing the "positive" syndrome of schizophrenia, carried serious motor side effects, such as immobility and Parkinsonism. While second-generation antipsychotics have reduced the incidence of such effects, they are not without risk. It has come to light that both first- and second-generation antipsychotics are associated with weight gain and type 2 diabetes. This short review addresses this issue, as well as covers recent studies to find which neurotransmitter receptors may be involved in the induction of these metabolic disturbances. (c) 2005 Prous Science. All rights reserved.