| Literature DB >> 163917 |
J Skare, W P Summers, W C Summers.
Abstract
The restriction endonuclease Eco R I cleaves HSV-1 and HSV-2 DNA into specific fragments that can be resolved by agarose gel electrophoresis. Comparison of HSV-1 strains KOS, 14-012, MP, F, and CI 101, and HSV-2 strains 333 and 186, suggests that the DNAs from type 1 strains are similar but not identical, and that the type 2 strains differ greatly from type 1 strains. The molecular lengths of the fragments have been determined by electron microscopy and can be used to calibrate gel electrophoretic analyses of DNA fragments.Entities:
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Year: 1975 PMID: 163917 PMCID: PMC354515
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103