Literature DB >> 16388660

"Click chemistry" inspired synthesis of pseudo-oligosaccharides and amino acid glycoconjugates.

Srinivas Hotha1, Sudhir Kashyap.   

Abstract

[reaction: see text] Various pseudo-oligosacchardies and amino acid glycoconjugates were synthesized via an intermolecular 1,3-dipolar cycloaddition ("click") reaction using easily accessible carbohydrate and amino acid derived azides and alkynes as building blocks. It is pertinent to mention that the conjugation reaction is highly regioselective and high yielding and can be carried out under mild reaction conditions.

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Year:  2006        PMID： 16388660     DOI： 10.1021/jo051731q

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  10 in total

1.  Sigmatropic rearrangements as tools for amino acid and peptide modification: application of the allylic sulfur ylide rearrangement to the preparation of neoglycoconjugates and other conjugates.

Authors:  David Crich; Yekui Zou; Franck Brebion
Journal:  J Org Chem       Date:  2006-11-24       Impact factor: 4.354

2.  Synthesis of function-oriented 2-phenyl-2H-chromene derivatives using L-pipecolinic acid and substituted guanidine organocatalysts.

Authors:  Bhaskar C Das; Seetaram Mohapatra; Philip D Campbell; Sabita Nayak; Sakkarapalayam M Mahalingam; Todd Evans
Journal:  Tetrahedron Lett       Date:  2010-05-01       Impact factor: 2.415

3.  Nicotinic acid adenine dinucleotide phosphate analogues containing substituted nicotinic acid: effect of modification on Ca(2+) release.

Authors:  Pooja Jain; James T Slama; Leroy A Perez-Haddock; Timothy F Walseth
Journal:  J Med Chem       Date:  2010-11-11       Impact factor: 7.446

4.  Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

Authors:  Sushil K Maurya; Deviprasad R Gollapalli; Shivapriya Kirubakaran; Minjia Zhang; Corey R Johnson; Nicole N Benjamin; Lizbeth Hedstrom; Gregory D Cuny
Journal:  J Med Chem       Date:  2009-08-13       Impact factor: 7.446

5.  Synthesis of neoglycoconjugates by the desulfurative rearrangement of allylic disulfides.

Authors:  David Crich; Fan Yang
Journal:  J Org Chem       Date:  2008-08-27       Impact factor: 4.354

6.  Significant rate accelerated synthesis of glycosyl azides and glycosyl 1,2,3-triazole conjugates.

Authors:  Rishi Kumar; Prakas R Maulik; Anup Kumar Misra
Journal:  Glycoconj J       Date:  2007-12-18       Impact factor: 2.916

7.  Design and synthesis of multivalent neoglycoconjugates by click conjugations.

Authors:  Feiqing Ding; Li Ji; Ronny William; Hua Chai; Xue-Wei Liu
Journal:  Beilstein J Org Chem       Date:  2014-06-10       Impact factor: 2.883

8.  Synthesis and Cytotoxic Activity of New 1,3,4-Thiadiazole Thioglycosides and 1,2,3-Triazolyl-1,3,4-Thiadiazole N-glycosides.

Authors:  Fahad M Alminderej; Hussein H Elganzory; Mohamed N El-Bayaa; Hanem M Awad; Wael A El-Sayed
Journal:  Molecules       Date:  2019-10-16       Impact factor: 4.411

9.  Click chemistry based synthesis, cytotoxic activity and molecular docking of novel triazole-thienopyrimidine hybrid glycosides targeting EGFR.

Authors:  Reham R Khattab; Asma K Alshamari; Allam A Hassan; Hussein H Elganzory; Wael A El-Sayed; Hanem M Awad; Eman S Nossier; Nasser A Hassan
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051

10.  In Vitro and In Vivo Antiviral Studies of New Heteroannulated 1,2,3-Triazole Glycosides Targeting the Neuraminidase of Influenza A Viruses.

Authors:  Omnia Kutkat; Ahmed Kandeil; Yassmin Moatasim; Yaseen A M M Elshaier; Wael A El-Sayed; Samir T Gaballah; Ahmed El Taweel; Mina Nabil Kamel; Mohamed El Sayes; Mohammed A Ramadan; Rabeh El-Shesheny; Farouk M E Abdel-Megeid; Richard Webby; Ghazi Kayali; Mohamed A Ali
Journal:  Pharmaceuticals (Basel)       Date:  2022-03-14
  10 in total

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