Literature DB >> 16388229

An unusual presentation of giant cell tumour (osteoclastoma).

E Pradhan1, J K Shrestha, P C K Karmacharya.   

Abstract

The number of well-documented true giant cell tumours arising in any of the craniofacial bones is small, but they do exist. A 19 year old female, Ms. KS, presented with complain of progressive enlargement of facial bones especially jaw bones, then orbit symmetrically since the age of 7. There was bilateral gross enlargement of mandible, maxilla, orbital walls, causing displacement of eye medially and upwards. The visual acuity of both eyes were 6/36 and 6/18 with best correction. Extra ocular movements were restricted because of bony growth and conjunctiva over inferior fornix were keratinized due to exposure. Fine needle aspiration (FNAC) from the side of bony growth showed plenty of osteoclasts with multinucleated giant cells. The level of serum alkaline phosphatase were highly increased. She underwent orbitotomy and a part of tissue was sent for biopsy which revealed multiples of mononucleargiant cells and tumour cells.

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Year:  2003        PMID: 16388229

Source DB:  PubMed          Journal:  Kathmandu Univ Med J (KUMJ)        ISSN: 1812-2027


  3 in total

1.  Giant cell tumor of bone: a neoplasm or a reactive condition?

Authors:  Anwar Ul Haque; Ambreen Moatasim
Journal:  Int J Clin Exp Pathol       Date:  2008-01-01

2.  Giant cell tumor of the mandible.

Authors:  G V V Giri; Gheena Sukumaran; C Ravindran; Malathi Narasimman
Journal:  J Oral Maxillofac Pathol       Date:  2015 Jan-Apr

3.  Palatal Swelling: A Diagnostic Enigma.

Authors:  Ramalingam Suganya; Narasimhan Malathi; Harikrishnan Thamizhchelvan; Subramaniam Ramkumar; G V V Giri
Journal:  Case Rep Dent       Date:  2016-11-16
  3 in total

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