BACKGROUND: Previous cross-sectional studies have highlighted a number of obstetric variables that may be associated with the development of broadly defined puerperal (post-partum) psychosis. These include: (a) primiparity, (b) pregnancy complications, (c) delivery complications, (d) Caesarean section, (e) female baby and (f) shorter gestation period. AIMS: To examine these risk factors in women with well-characterised bipolar affective puerperal psychosis. METHOD: A sample of 129 women with bipolar affective puerperal psychosis were investigated using a design that takes advantage of within-subject comparisons of affected and unaffected deliveries. RESULTS: Two of the variables studied were independently associated with an episode of puerperal psychosis: primiparity (odds ratio=3.76, P < 0.001) and delivery complications (odds ratio=2.68, P=0.022). CONCLUSIONS: This study provides further evidence of the association between primiparity and puerperal psychosis and suggests that complications during delivery may be associated with a severe post-partum episode.
BACKGROUND: Previous cross-sectional studies have highlighted a number of obstetric variables that may be associated with the development of broadly defined puerperal (post-partum) psychosis. These include: (a) primiparity, (b) pregnancy complications, (c) delivery complications, (d) Caesarean section, (e) female baby and (f) shorter gestation period. AIMS: To examine these risk factors in women with well-characterised bipolar affective puerperal psychosis. METHOD: A sample of 129 women with bipolar affective puerperal psychosis were investigated using a design that takes advantage of within-subject comparisons of affected and unaffected deliveries. RESULTS: Two of the variables studied were independently associated with an episode of puerperal psychosis: primiparity (odds ratio=3.76, P < 0.001) and delivery complications (odds ratio=2.68, P=0.022). CONCLUSIONS: This study provides further evidence of the association between primiparity and puerperal psychosis and suggests that complications during delivery may be associated with a severe post-partum episode.
Authors: Emma Robertson Blackmore; David R Rubinow; Thomas G O'Connor; Xiang Liu; Wan Tang; Nick Craddock; Ian Jones Journal: Bipolar Disord Date: 2013-05-07 Impact factor: 6.744
Authors: Chloe E Mighton; Angela J Inglis; Prescilla B Carrion; Catriona L Hippman; Emily M Morris; Heather J Andrighetti; Rolan Batallones; William G Honer; Jehannine C Austin Journal: Arch Womens Ment Health Date: 2015-08-11 Impact factor: 3.633