BACKGROUND: Long-term survival after heart transplantation is a desirable although challenging goal. METHODS: We analyzed clinical outcomes in the cohort of 170 patients who have undergone heart transplantation at The Cleveland Clinic Foundation and survived >10 years. RESULTS: We found 10-year and 15-year survival rates of 54% and 41%, respectively, in these patients, but there was also a high incidence of complications, such as hypertension, renal dysfunction, transplant vasculopathy, and malignancy. CONCLUSIONS: Long-term survival following cardiac transplantation is possible although complications are frequent. Beyond 10 years, malignancy is a major cause of death.
BACKGROUND: Long-term survival after heart transplantation is a desirable although challenging goal. METHODS: We analyzed clinical outcomes in the cohort of 170 patients who have undergone heart transplantation at The Cleveland Clinic Foundation and survived >10 years. RESULTS: We found 10-year and 15-year survival rates of 54% and 41%, respectively, in these patients, but there was also a high incidence of complications, such as hypertension, renal dysfunction, transplant vasculopathy, and malignancy. CONCLUSIONS: Long-term survival following cardiac transplantation is possible although complications are frequent. Beyond 10 years, malignancy is a major cause of death.
Authors: Nicola Vistarini; Anthony Nguyen; Michel White; Normand Racine; Louis P Perrault; Anique Ducharme; Denis Bouchard; Philippe Demers; Michel Pellerin; Yoan Lamarche; Ismaïl El-Hamamsy; Geneviève Giraldeau; Guy Pelletier; Michel Carrier Journal: Can J Surg Date: 2017-09 Impact factor: 2.089
Authors: A Sammani; A M Wind; J H Kirkels; C Klöpping; M P Buijsrogge; F Z Ramjakhan; F W Asselbergs; N de Jonge Journal: Neth Heart J Date: 2017-09 Impact factor: 2.380