Literature DB >> 163864

Release of cyclic AMP from macrophages by stimulation with prostaglandins.

D Gemsa, L Steggemann, J Menzel, G Till.   

Abstract

The effect of various prostaglandins (PG)on the generation of cyclic AMP in rat peritoneal macrophages has been studied in vitro. PGE1 produced a rapid intracellular accumulation of cyclic AMP which was followed by its release into the extracellular space. More cyclic AMP was released with prostaglandins of the E-type than with A- and F-types. It is suggested that release of cyclic AMP from macrophages may participate in the modulation of leukocyte function.

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Year:  1975        PMID： 163864

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  13 in total

1.  Human immunoglobulin preparation for intravenous use induces elevation of cellular cyclic adenosine 3':5'-monophosphate levels, resulting in suppression of tumour necrosis factor alpha and interleukin-1 production.

Authors:  T Shimozato; M Iwata; H Kawada; N Tamura
Journal:  Immunology       Date:  1991-04       Impact factor: 7.397

2.  Prostaglandin regulation of macrophage collagenase production.

Authors:  L M Wahl; C E Olsen; A L Sandberg; S E Mergenhagen
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

3.  Extracellular hydrolytic enzymes of rabbit dermal tuberculous lesions and tuberculin reactions collected in skin chambers.

Authors:  M Sugimoto; A M Dannenberg; L M Wahl; W H Ettinger; A T Hastie; D C Daniels; C R Thomas; L Demoulin-Brahy
Journal:  Am J Pathol       Date:  1978-03       Impact factor: 4.307

4.  Cyclic AMP and prostaglandin E in perfusates of rat hind paws during the development of adjuvant arthritis.

Authors:  M J Parnham; I L Bonta; M J Adolfs
Journal:  Ann Rheum Dis       Date:  1978-06       Impact factor: 19.103

Review 5.  Mononuclear phagocytes and eicosanoids: aspects of their synthesis and biological activities.

Authors:  U F Schade; I Burmeister; E Elekes; R Engel; D T Wolter
Journal:  Blut       Date:  1989-12

6.  Early biochemical reactions in the lung of sheep exposed to asbestos: evidence for cyclic AMP accumulation in bronchoalveolar lavage fluids.

Authors:  I Lemaire; P Sirois; M Rola-Pleszczynski; S Massé; R Bégin
Journal:  Lung       Date:  1981       Impact factor: 2.584

7.  Synthesis and release of oxygenation products of arachidonic acid by mononuclear phagocytes in response to inflammatory stimuli.

Authors:  P Davies; R J Bonney; J L Humes; F A Kuehl
Journal:  Inflammation       Date:  1977-12       Impact factor: 4.092

8.  Enhancement by cyclo-oxygenase inhibitors of platelet-activating factor production in thapsigargin-stimulated macrophages.

Authors:  M Watanabe; M Yamada; S Mue; K Ohuchi
Journal:  Br J Pharmacol       Date:  1995-10       Impact factor: 8.739

9.  Macrophages as targets of inhibitory effects of E-type prostaglandins in immune-related inflammation.

Authors:  I L Bonta; M J Parnham
Journal:  Agents Actions       Date:  1981-12

10.  Differential effects of prostaglandin E2 and cyclic AMP on release of arachidonic acid metabolites from resting and lipopolysaccharide-stimulated macrophages.

Authors:  N Feuerstein; P W Ramwell
Journal:  Br J Pharmacol       Date:  1984-11       Impact factor: 8.739
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