Literature DB >> 16386353

Prevalence of Peyronie's disease among patients with erectile dysfunction.

Ahmed I El-Sakka1.   

Abstract

PURPOSE: To assess the prevalence of Peyronie's disease (PD) among patients with erectile dysfunction (ED).
MATERIALS AND METHODS: A total of 1,440 male patients with ED were enrolled in this study. Patients were interviewed for ED using the International Index of Erectile Function (IIEF). All patients were also screened for socio-demographic data and risk factors for ED that included age, smoking, diabetes, hypertension, dyslipidemia, Ischemic Heart Disease (IHD), and psychological disorders. The diagnosis of PD was based on a palpable penile plaque or acquired penile curvature. Patients underwent routine laboratory investigation in addition to testosterone and prolactin assessment.
RESULTS: Mean ages +/-SD were 54.1 +/- 6.9 (range 42-71) and 52.5 +/- 11.9 (range 20-84) years for patients with and without PD respectively. Of the patients, 11.8% had mild, 38.3% had moderate and 49.9% had severe ED. 7.9% of the patients had PD. Significant associations between PD and both the longer duration and the increased severity of ED were detected. There were also significant associations between PD and the following socio-demographic risk factors of ED: age, obesity, smoking, duration and number of cigarettes smoked per day. Concomitant diseases and medical comorbidities such as diabetes, dyslipidemia, psychological disorders and the presence of at least one risk factor were significantly associated with PD in patients with ED.
CONCLUSIONS: Peyronie's disease was not rare among the study population. There were significant associations between ED risk factors and PD. Further studies are needed to investigate how much ED and PD influence each other.

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Year:  2005        PMID: 16386353     DOI: 10.1016/j.eururo.2005.10.026

Source DB:  PubMed          Journal:  Eur Urol        ISSN: 0302-2838            Impact factor:   20.096


  21 in total

1.  PEYRONIE'S DISEASE: A REVIEW OF ETIOLOGY, DIAGNOSIS, AND MANAGEMENT.

Authors:  Aylin N Bilgutay; Alexander W Pastuszak
Journal:  Curr Sex Health Rep       Date:  2015-06-01

2.  Update on plication procedures for Peyronie's disease and other penile deformities.

Authors:  Elizabeth M Mobley; Molly E Fuchs; Jeremy B Myers; William O Brant
Journal:  Ther Adv Urol       Date:  2012-12

3.  Testosterone Levels Are Not Associated With Magnitude of Deformity in Men With Peyronie's Disease.

Authors:  John P Mulhall; Kazuhito Matsushita; Christian J Nelson
Journal:  J Sex Med       Date:  2019-07-11       Impact factor: 3.802

Review 4.  Testosterone replacement therapy and erectile dysfunction.

Authors:  Ifeanyi C Onyeji; Raul I Clavijo
Journal:  Int J Impot Res       Date:  2022-01-08       Impact factor: 2.896

5.  Evaluating the efficacy of intraplaque injection of dexamethasone with oral tadalafil in the chordee patients with Peyronie disease.

Authors:  Mohammad Hatampour; Karim Sohrabi; Hamid Mazdak; Keyvan Ghadimi; Hanieh Salehi; Reza Kazemi
Journal:  Am J Clin Exp Urol       Date:  2022-02-15

6.  Significant familial clustering of Peyronie's disease in close and distant relatives.

Authors:  Kristina L Allen-Brady; Michael B Christensen; Ashlynn D Sandberg; Alexander W Pastuszak
Journal:  Andrology       Date:  2022-07-13       Impact factor: 4.456

7.  Erectile dysfunction and Peyronie's disease in patient with retroperitoenal fibrosis.

Authors:  Cem Akbal; Yilören Tanidir; Mahir Bülent Ozgen; Ferruh Simşek
Journal:  Int Urol Nephrol       Date:  2008-04-24       Impact factor: 2.370

Review 8.  The Natural History of Peyronie's Disease.

Authors:  Fabrizio Di Maida; Gianmartin Cito; Luca Lambertini; Francesca Valastro; Girolamo Morelli; Andrea Mari; Marco Carini; Andrea Minervini; Andrea Cocci
Journal:  World J Mens Health       Date:  2020-07-08       Impact factor: 5.400

9.  A Population-Based Study of Peyronie's Disease: Prevalence and Treatment Patterns in the United States.

Authors:  Dana Britt Dibenedetti; Dat Nguyen; Laurie Zografos; Ryan Ziemiecki; Xiaolei Zhou
Journal:  Adv Urol       Date:  2011-10-23

Review 10.  A critical analysis of the surgical outcomes for the treatment of Peyronie's disease.

Authors:  Sree H Mandava; Landon W Trost; Wayne J G Hellstrom
Journal:  Arab J Urol       Date:  2013-05-06
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