Literature DB >> 16384754

The epidemiology of molluscum contagiosum in children.

Magdalene A Dohil1, Peggy Lin, James Lee, Anne W Lucky, Amy S Paller, Lawrence F Eichenfield.   

Abstract

Molluscum contagiosum (MC) is a viral disorder of the skin and mucous membranes characterized by discrete single or multiple, flesh-colored papules. Although MC as a clinical entity is well defined and commonly observed, few data regarding its epidemiology in the pediatric population exist. Our purpose was to collect epidemiologic data on children with MC with regard to age, gender, ethnicity, degree of involvement, relation to pre-existing atopic dermatitis (AD), and immune status. A retrospective chart review was conducted. All subjects were seen at 3 tertiary pediatric dermatology referral centers with two of the sites based at a Children's Hospital. A total of 302 patient charts with the Current Procedural Terminology code diagnosis of MC seen over a 6- to 8-month period were reviewed. Approximately 80% of the patients were younger than 8 years old. The majority of patients (63%) had more than 15 lesions. All but one patient were otherwise healthy, as determined by history and clinical examination. Approximately 24% of the patients presented with a history of previous or active coexistent AD. However, children with AD were at risk for an increased number of lesions. These data provide valuable updated information on the demographics and clinical presentation of MC in pediatric patients in the United States. Limitations include that this was a retrospective study with a population limited to tertiary pediatric dermatology referral centers.

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Year:  2005        PMID: 16384754     DOI: 10.1016/j.jaad.2005.08.035

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  20 in total

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4.  Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells.

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5.  Solitary giant molluscum contagiosum presenting as lid tumor in an immunocompetent child.

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6.  Disseminated molluscum contagiosum in a HIV-positive child. Improvement after therapy with 5% imiquimod.

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7.  Extensive Giant Molluscum Contagiosum in a HIV Positive Patient.

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Review 8.  The infectious aspects of atopic dermatitis.

Authors:  Peck Y Ong; Donald Y M Leung
Journal:  Immunol Allergy Clin North Am       Date:  2010-07-01       Impact factor: 3.479

9.  The Incidence of Molluscum contagiosum among American Indians and Alaska Natives.

Authors:  Mary G Reynolds; Robert C Holman; Krista L Yorita Christensen; James E Cheek; Inger K Damon
Journal:  PLoS One       Date:  2009-04-21       Impact factor: 3.240

10.  Molluscum contagiosum and associations with atopic eczema in children: a retrospective longitudinal study in primary care.

Authors:  Jonathan R Olsen; Vincent Piguet; John Gallacher; Nick A Francis
Journal:  Br J Gen Pract       Date:  2015-12-06       Impact factor: 5.386

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