Literature DB >> 16382967

Surgical management of substernal goitres. When is sternotomy inevitable?

G Flati1, T De Giacomo, B Porowska, D Flati, F Gaj, C Talarico, F Antonellis, M Diana, P B Berloco.   

Abstract

PURPOSE: Aim of this retrospective study is to report personal experience in the surgical management of substernal goitres emphasizing the guidelines for preoperative planning of sternotomy in selected cases. PATIENTS AND METHODS: Medical records of all patients (n=355) submitted to thyroidectomy for struma in our Operative Unit, between 1993-2003, were analysed. A substernal goitre was defined as a goitre having a significant retrosternal extension (>50%) requiring mediastinal dissection.
RESULTS: A total of 18 out of 355 patients undergoing thyroidectomy for struma in our Operative Unit had substernal goitres. The most common symptoms, at presentation, were the presence of neck mass and respiratory disorders. Standard cervical incision was adequate to achieve total thyroidectomy in 17 cases while, in one patient with computed tomography images showing the presence of a huge goitre extending below the aortic arch, a sternotomic approach was inevitable to ensure safe removal. No major morbidity or perioperative deaths occurred. One patient with scleroderma experienced bilateral paralysis of laryngeal nerves for two months, with full recovery thereafter.
CONCLUSIONS: While removal of the majority of substernal goitres can be achieved by means of cervical incision, this approach is not always safe. In a selected number of cases with an iceberg shaped substernal goiter and with >70% of the volume lying below the thoracic outlet, a sternotomic approach is inevitable. Preoperative diagnostic work-up should, thus, include chest X-ray and computed tomography. Overall results in the present patient population, have been excellent since morbidity has been minimal and mortality absent, and all patients are symptom free.

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Year:  2005        PMID: 16382967

Source DB:  PubMed          Journal:  Clin Ter        ISSN: 0009-9074


  13 in total

Review 1.  Surgical approach to the substernal goiter.

Authors:  Martin A Hanson; Ashok R Shaha; James X Wu
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2019-08-22       Impact factor: 4.690

2.  Surgical approach to retrosternal goitre: do we still need sternotomy?

Authors:  M G Rugiu; M Piemonte
Journal:  Acta Otorhinolaryngol Ital       Date:  2009-12       Impact factor: 2.124

Review 3.  Diagnosis and management of substernal goiter at the University of Crete.

Authors:  John Bizakis; Alexandros Karatzanis; Jiannis Hajiioannou; Constantinos Bourolias; Eleutherios Maganas; Elias Spanakis; Argyro Bizaki; George Velegrakis
Journal:  Surg Today       Date:  2008-02-01       Impact factor: 2.549

4.  Evidence-based surgical management of substernal goiter.

Authors:  Matthew L White; Gerard M Doherty; Paul G Gauger
Journal:  World J Surg       Date:  2008-07       Impact factor: 3.352

5.  RETROSTERNAL GOITRES: A PRACTICAL CLASSIFICATION.

Authors:  I T Cvasciuc; S Fraser; M Lansdown
Journal:  Acta Endocrinol (Buchar)       Date:  2017 Jul-Sep       Impact factor: 0.877

6.  Surgical management of retrosternal goiter: Local experience at a university hospital.

Authors:  Gamal A Khairy; Abdulaziz A Al-Saif; Sami A Alnassar; Waseem M Hajjar
Journal:  Ann Thorac Med       Date:  2012-04       Impact factor: 2.219

7.  Myasthenic Crisis Manifesting as Postoperative Respiratory Failure following Resection of Unsuspected Intrathoracic Thymic T-Cell Lymphoma during Thyroidectomy for an Adjacent Large Retrosternal Goiter.

Authors:  Mohamed E Ahmed; Mohamed A Mahgoub; Mohamed G Alnedar; Seif I Mahadi; Maha Alzubeir; Lamyaa A M El Hassan; ElWaleed M Elamin; Ahmed Mohammed El Hassan
Journal:  Eur Thyroid J       Date:  2014-08-09

8.  Patient-tailored management of an asymptomatic massive substernal goiter presenting as brachiocephalic vein occlusion. Report of a case and review of sternotomy indications.

Authors:  Georgios Sahsamanis; Eleftherios Chouliaras; Konstantinos Katis; Stavros Samaras; Stavros Daliakopoulos; Georgios Dimitrakopoulos
Journal:  Int J Surg Case Rep       Date:  2017-01-04

9.  Thyroiditis process as a predictive factor of sternotomy in the treatment of cervico-mediastinal goiter.

Authors:  Claudio Casella; Sarah Molfino; Carlo Cappelli; Federica Salvoldi; Mauro Roberto Benvenuti; Nazario Portolani
Journal:  BMC Surg       Date:  2019-04-24       Impact factor: 2.102

10.  Substernal goiter: when is a sternotomy required?

Authors:  Ali Coskun; Mehmet Yildirim; Nazif Erkan
Journal:  Int Surg       Date:  2014 Jul-Aug
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