Literature DB >> 1638120

Mechanisms of liver-specific gene expression.

F M Sladek1, J E Darnell.   

Abstract

Significant advances in the field of hepatocyte-specific gene expression have been made during the past year. Several new transcription factors have been cloned and partially characterized. Analyses of the promoter regions of several factors have also been initiated and Drosophila homologs for two of these factors have been found, opening the way for studies on development.

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Year:  1992        PMID: 1638120     DOI: 10.1016/s0959-437x(05)80282-5

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN: 0959-437X            Impact factor:   5.578


  18 in total

1.  E.B. Wilson Lecture, 1998. Eukaryotic RNAs: once more from the beginning.

Authors:  J E Darnell
Journal:  Mol Biol Cell       Date:  1999-06       Impact factor: 4.138

2.  Changes in Gene Expression and Estrogen Receptor Cistrome in Mouse Liver Upon Acute E2 Treatment.

Authors:  Gaëlle Palierne; Aurélie Fabre; Romain Solinhac; Christine Le Péron; Stéphane Avner; Françoise Lenfant; Coralie Fontaine; Gilles Salbert; Gilles Flouriot; Jean-François Arnal; Raphaël Métivier
Journal:  Mol Endocrinol       Date:  2016-05-10

3.  Med25 is required for RNA polymerase II recruitment to specific promoters, thus regulating xenobiotic and lipid metabolism in human liver.

Authors:  Ritu Rana; Sailesh Surapureddi; Waynekid Kam; Stephen Ferguson; Joyce A Goldstein
Journal:  Mol Cell Biol       Date:  2010-12-06       Impact factor: 4.272

4.  NCOA6 differentially regulates the expression of the CYP2C9 and CYP3A4 genes.

Authors:  Sailesh Surapureddi; Ritu Rana; Joyce A Goldstein
Journal:  Pharmacol Res       Date:  2011-02-01       Impact factor: 7.658

5.  High level activity of the mouse CCAAT/enhancer binding protein (C/EBP alpha) gene promoter involves autoregulation and several ubiquitous transcription factors.

Authors:  C Legraverend; P Antonson; P Flodby; K G Xanthopoulos
Journal:  Nucleic Acids Res       Date:  1993-04-25       Impact factor: 16.971

6.  The distal enhancer implicated in the developmental regulation of the tyrosine aminotransferase gene is bound by liver-specific and ubiquitous factors.

Authors:  D Nitsch; G Schütz
Journal:  Mol Cell Biol       Date:  1993-08       Impact factor: 4.272

7.  Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes.

Authors:  T Drewes; S Senkel; B Holewa; G U Ryffel
Journal:  Mol Cell Biol       Date:  1996-03       Impact factor: 4.272

8.  Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst.

Authors:  S A Duncan; K Manova; W S Chen; P Hoodless; D C Weinstein; R F Bachvarova; J E Darnell
Journal:  Proc Natl Acad Sci U S A       Date:  1994-08-02       Impact factor: 11.205

9.  Competition between transcription factors HNF1 and HNF3, and alternative cell-specific activation by DBP and C/EBP contribute to the regulation of the liver-specific aldolase B promoter.

Authors:  C Gregori; A Kahn; A L Pichard
Journal:  Nucleic Acids Res       Date:  1993-02-25       Impact factor: 16.971

10.  Elements and factors involved in tissue-specific and embryonic expression of the liver transcription factor LFB1 in Xenopus laevis.

Authors:  D Zapp; S Bartkowski; B Holewa; C Zoidl; L Klein-Hitpass; G U Ryffel
Journal:  Mol Cell Biol       Date:  1993-10       Impact factor: 4.272

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