Literature DB >> 16381080

Constructing binomial confidence intervals with near nominal coverage by adding a single imaginary failure or success.

Craig B Borkowf1.   

Abstract

In this paper we present a simple method for constructing (1- alpha)100 per cent confidence intervals for binomial proportions with near nominal coverage for all underlying proportion parameters on the unit interval. This new method uses, with a slight modification, the standard normal approximation technique taught in introductory statistics classes. Specifically, we first augment the observed binomial data with an imaginary failure to compute the lower bound and an imaginary success to compute the upper bound. By contrast, the Agresti-Coull method adds the same number of imaginary successes and failures to the observed data, yet it can still give somewhat subnominal coverage. As motivation, we discuss the relationship between this new method and the Clopper-Pearson exact method. We also present numerical calculations to illustrate the satisfactory performance of this new method compared with several common alternatives. Finally, we argue that for certain statistical applications, such as the design and analysis of clinical trials with adverse events, this new method represents a valuable complementary approach.

Entities:  

Mesh:

Year:  2006        PMID: 16381080     DOI: 10.1002/sim.2469

Source DB:  PubMed          Journal:  Stat Med        ISSN: 0277-6715            Impact factor:   2.373


  5 in total

1.  Evaluation of vaccine seroresponse rates and adverse event rates through Bayesian and frequentist methods.

Authors:  Jin Liu; Feng Chen; Feng-Cai Zhu; Jian-Ling Bai; Jing-Xin Li; Hao Yu; Pei Liu; Ping Zeng
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

2.  Multilocus sequence typing of genital Chlamydia trachomatis in Norway reveals multiple new sequence types and a large genetic diversity.

Authors:  Kirsten Gravningen; Linus Christerson; Anne-Sofie Furberg; Gunnar Skov Simonsen; Kristina Ödman; Anna Ståhlsten; Björn Herrmann
Journal:  PLoS One       Date:  2012-03-28       Impact factor: 3.240

3.  Chlamydia trachomatis Strain Types Have Diversified Regionally and Globally with Evidence for Recombination across Geographic Divides.

Authors:  Vitaly Smelov; Alison Vrbanac; Eleanne F van Ess; Marlies P Noz; Raymond Wan; Carina Eklund; Tyler Morgan; Lydia A Shrier; Blake Sanders; Joakim Dillner; Henry J C de Vries; Servaas A Morre; Deborah Dean
Journal:  Front Microbiol       Date:  2017-11-13       Impact factor: 5.640

Review 4.  Statistical methods for the analysis of adverse event data in randomised controlled trials: a scoping review and taxonomy.

Authors:  Rachel Phillips; Odile Sauzet; Victoria Cornelius
Journal:  BMC Med Res Methodol       Date:  2020-11-30       Impact factor: 4.615

Review 5.  Mortality and survival in idiopathic pulmonary fibrosis: a systematic review and meta-analysis.

Authors:  Qiang Zheng; Ingrid A Cox; Julie A Campbell; Qing Xia; Petr Otahal; Barbara de Graaff; Tamera J Corte; Alan K Y Teoh; E Haydn Walters; Andrew J Palmer
Journal:  ERJ Open Res       Date:  2022-03-14
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.