| Literature DB >> 16380817 |
Kouetsu Ogasawara1, Lewis L Lanier.
Abstract
One of the best characterized NK cell receptors is NKG2D, a highly conserved C-type lectin-like membrane glycoprotein expressed on essentially all NK cells, as well as on gammadelta-TcR+ T cells and alphabeta-TcR+ CD8+ T cells, in humans and mice. Here we review recent studies implicating NKG2D in T cell and NK cell-mediated immunity to viruses and tumors, and its potential role in autoimmune diseases and allogeneic bone marrow transplantation.Entities:
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Year: 2005 PMID: 16380817 DOI: 10.1007/s10875-005-8786-4
Source DB: PubMed Journal: J Clin Immunol ISSN: 0271-9142 Impact factor: 8.317