| Literature DB >> 16380256 |
Xiaoyan Zhang1, Maud Urbanski, Mona Patel, Geoffrey G Cox, Roxanne E Zeck, Haiyan Bian, Bruce R Conway, Mary Pat Beavers, Philip J Rybczynski, Keith T Demarest.
Abstract
A series of indole-O-glucosides and C-glucosides was synthesized and evaluated in SGLT1 and SGLT2 cell-based functional assays. Compounds 2a and 2o were identified as potent SGLT2 inhibitors and screened in ZDF rats.Entities:
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Year: 2005 PMID： 16380256 DOI： 10.1016/j.bmcl.2005.12.006
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823