Literature DB >> 16378363

Antiviral Terpenoid Constituents of Ganoderma pfeifferi.

Timo H J Niedermeyer1, Ulrike Lindequist, Renate Mentel, Dirk Gördes, Enrico Schmidt, Kerstin Thurow, Michael Lalk.   

Abstract

Four sterols and 10 triterpenes were isolated from the fruiting bodies of Ganoderma pfeifferi, including the three new triterpenes 3,7,11-trioxo-5alpha-lanosta-8,24-diene-26-al (lucialdehyde D, 1), 5alpha-lanosta-8,24-diene-26-hydroxy-3,7-dione (ganoderone A, 2), and 5alpha-lanosta-8-ene-24,25-epoxy-26-hydroxy-3,7-dione (ganoderone C, 3). The structures of 1-3 were determined on the basis of spectroscopic evidence. Antibacterial, antifungal, and antiviral activity were studied for some of the isolated compounds. Ganoderone A (2), lucialdehyde B (4), and ergosta-7,22-dien-3beta-ol (7) were found to exhibit potent inhibitory activity against herpes simplex virus.

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Year:  2005        PMID： 16378363     DOI： 10.1021/np0501886

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  20 in total

Review 1.  Mushrooms: an emerging resource for therapeutic terpenoids.

Authors:  Adhiraj Dasgupta; Krishnendu Acharya
Journal:  3 Biotech       Date:  2019-09-24       Impact factor: 2.406

2.  Attenuation of Leishmania infantum chagasi metacyclic promastigotes by sterol depletion.

Authors:  Chaoqun Yao; Upasna Gaur Dixit; Jason H Barker; Lynn M Teesch; Laurie Love-Homan; John E Donelson; Mary E Wilson
Journal:  Infect Immun       Date:  2013-04-29       Impact factor: 3.441

Review 3.  Accessing biological actions of Ganoderma secondary metabolites by in silico profiling.

Authors:  Ulrike Grienke; Teresa Kaserer; Florian Pfluger; Christina E Mair; Thierry Langer; Daniela Schuster; Judith M Rollinger
Journal:  Phytochemistry       Date:  2014-11-06       Impact factor: 4.072

4.  Antiviral activity of monoterpenes beta-pinene and limonene against herpes simplex virus in vitro.

Authors:  Akram Astani; Paul Schnitzler
Journal:  Iran J Microbiol       Date:  2014-06

5.  Improvement of Ergone Production from Mycelial Culture of Polyporus umbellatus.

Authors:  Wi Young Lee; Youngki Park; Jin Kwon Ahn
Journal:  Mycobiology       Date:  2007-06-30       Impact factor: 1.858

Review 6.  Antimicrobial Properties of Plant Essential Oils against Human Pathogens and Their Mode of Action: An Updated Review.

Authors:  Mallappa Kumara Swamy; Mohd Sayeed Akhtar; Uma Rani Sinniah
Journal:  Evid Based Complement Alternat Med       Date:  2016-12-20       Impact factor: 2.629

7.  Chemical Composition, Antimicrobial and Antioxidant Activities of the Volatile Oil of Ganoderma pfeifferi Bres.

Authors:  Mohamed Al-Fatimi; Martina Wurster; Ulrike Lindequist
Journal:  Medicines (Basel)       Date:  2016-04-28

8.  Antiviral activity of some plants used in Nepalese traditional medicine.

Authors:  M Rajbhandari; R Mentel; P K Jha; R P Chaudhary; S Bhattarai; M B Gewali; N Karmacharya; M Hipper; U Lindequist
Journal:  Evid Based Complement Alternat Med       Date:  2007-10-25       Impact factor: 2.629

9.  Screening for antiviral activities of isolated compounds from essential oils.

Authors:  Akram Astani; Jürgen Reichling; Paul Schnitzler
Journal:  Evid Based Complement Alternat Med       Date:  2011-02-14       Impact factor: 2.629

10.  Dynamics of sterol synthesis during development of Leishmania spp. parasites to their virulent form.

Authors:  Chaoqun Yao; Mary E Wilson
Journal:  Parasit Vectors       Date:  2016-04-12       Impact factor: 3.876
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