Literature DB >> 16378236

Eosinophilic cytoplasmic inclusions in papillary renal cell carcinoma.

Naoyuki Danbara1, Nobuaki Shikata, Hiroshi Kawamura, Masayuki Shintaku, Airo Tsubura.   

Abstract

A case of a patient with papillary renal cell carcinoma (RCC) with eosinophilic inclusions is presented. Almost all neoplastic cells contained eosinophilic globules that were stained red by trichrome and were negative for periodic acid-Schiff (PAS) reaction. Immunohistochemically, globules were negative for actin, keratin, vimentin, glially fibrillary acidic protein (GFAP), and neurofilament. Ultrastructurally, globules consisted of electron-dense granular material that is more suggestive of a secretory substance than cytoskeletal filaments. The presence of eosinophilic cytoplasmic inclusions in RCC is rare. In this article, we review similar cases in the literature and discuss the nature of eosinophilic globules.

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Year:  2005        PMID： 16378236     DOI： 10.1007/s00795-005-0286-3

Source DB:  PubMed          Journal:  Med Mol Morphol        ISSN： 1860-1499            Impact factor:   2.309


  15 in total

1.  Renal cell carcinoma with rhabdoid features: an aggressive neoplasm.

Authors:  K Kuroiwa; Y Kinoshita; H Shiratsuchi; Y Oshiro; S Tamiya; Y Oda; S Naito; M Tsuneyoshi
Journal:  Histopathology       Date:  2002-12       Impact factor: 5.087

2.  Immunohistochemical profiles of Mallory body by a panel of anti-cytokeratin antibodies.

Authors:  Ren-Jeng Pei; Naoyuki Danbara; Miki Tsujita-Kyutoku; Takashi Yuri; Airo Tsubura
Journal:  Med Electron Microsc       Date:  2004-06

3.  Renal epithelial neoplasms: the diagnostic implications of electron microscopic study in 55 cases.

Authors:  Bhuvaneswari Krishnan; Luan D Truong
Journal:  Hum Pathol       Date:  2002-01       Impact factor: 3.466

4.  Hyaline globules in renal cell carcinomas and oncocytomas.

Authors:  Z Gatalica; M Miettinen; A Kovatich; P A McCue
Journal:  Hum Pathol       Date:  1997-04       Impact factor: 3.466

5.  Hyaline intracytoplasmic globules in renal carcinoma.

Authors:  B N Datta
Journal:  Arch Pathol Lab Med       Date:  1977-07       Impact factor: 5.534

6.  Case for the panel. Unique intracytoplasmic inclusion in a probable granular renal cell carcinoma metastasis.

Authors:  P H Carstens; G A Herrera; E A Turbat-Herrera; C M Listinsky; K Levesque
Journal:  Ultrastruct Pathol       Date:  1995 May-Jun       Impact factor: 1.094

Review 7.  The ultrastructure and immunocytochemistry of renal cell carcinoma.

Authors:  B Mackay; N G Ordónez; J Khoursand; J L Bennington
Journal:  Ultrastruct Pathol       Date:  1987       Impact factor: 1.094

8.  Renal oncocytoma: diagnostic utility of cytokeratin-containing globular filamentous bodies.

Authors:  S M Bonsib; C Bromley; D J Lager
Journal:  Mod Pathol       Date:  1991-01       Impact factor: 7.842

9.  Glassy hyaline globules in granular cell carcinoma, chromophobe cell carcinoma, and oncocytoma of the kidney.

Authors:  O Hes; M Michal; M Sulc; L Kocová; M Hora; M Rousarová
Journal:  Ann Diagn Pathol       Date:  1998-02       Impact factor: 2.090

10.  Myelinoid lamellated cytoplasmic inclusions in human renal adenocarcinomas: an ultrastructural study.

Authors:  M T Hull; J N Eble
Journal:  Ultrastruct Pathol       Date:  1988 Jan-Feb       Impact factor: 1.094
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  7 in total

1.  Signet-ring stromal tumor of the ovary: an immunohistochemical and ultrastructural study with a review of the literature.

Authors:  Manabu Matsumoto; Yoshihiro Hayashi; Yuji Ohtsuki; Nobuo Ikegami; Makoto Toi; Mitsuko Iguchi; Makoto Hiroi
Journal:  Med Mol Morphol       Date:  2008-09-20       Impact factor: 2.309

2.  Sporadic renal hemangioblastoma with CA9, PAX2 and PAX8 expression: diagnostic pitfall in the differential diagnosis from clear cell renal cell carcinoma.

Authors:  Naoto Kuroda; Yoshiko Agatsuma; Masato Tamura; Petr Martinek; Ondrej Hes; Michal Michal
Journal:  Int J Clin Exp Pathol       Date:  2015-02-01

3.  Hyaline globule-like structures in undifferentiated sarcoma cells of malignant müllerian mixed tumor of the fallopian tube.

Authors:  Naoto Kuroda; Yasunobu Inui; Masahiko Ohara; Takashi Hirouchi; Keiko Mizuno; Ayumi Kubo; Yoshihiro Hayashi; Hideaki Enzan; Gang-Hong Lee
Journal:  Med Mol Morphol       Date:  2007-03-29       Impact factor: 2.309

4.  Anaplastic carcinoma of the pancreas with rhabdoid features and hyaline globule-like structures.

Authors:  Naoto Kuroda; Shin-Ichi Iwamura; Nokiaki Fujishima; Masahiko Ohara; Takashi Hirouchi; Keiko Mizuno; Yoshihiro Hayashi; Gang-Hong Lee
Journal:  Med Mol Morphol       Date:  2007-09-18       Impact factor: 2.309

5.  Undifferentiated laryngeal carcinoma with hyaline bodies in a cat.

Authors:  Filippo Torrigiani; Maria Elena Gelain; Laura Cavicchioli; Roberta Di Maggio; Tommaso Banzato; Federico Bonsembiante
Journal:  Acta Vet Scand       Date:  2021-11-22       Impact factor: 1.695

Review 6.  Eosinophilic cytoplasmic inclusions in type 2 papillary renal cell carcinoma.

Authors:  M Ungari; M Trombatore; G Ferrero; M D Gusolfino; L Manotti; G Tanzi; E Varotti; R Bertoni
Journal:  Pathologica       Date:  2019-12

7.  Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.

Authors:  Zhou Yu; Jing Ma; Xia Li; Yixiong Liu; Mingyang Li; Lu Wang; Ming Zhao; Huiying He; Yifen Zhang; Qiu Rao; Danhui Zhao; Yingmei Wang; Linni Fan; Peifeng Li; Yang Liu; Fang Liu; Feng Zhang; Jing Ye; Qingguo Yan; Shuangping Guo; Zhe Wang
Journal:  Sci Rep       Date:  2018-07-02       Impact factor: 4.379
  7 in total

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