Literature DB >> 16378162

Multi-chamber intracardiac thrombi associated with activated protein C resistance in a patient with dilated cardiomyopathy.

Mucahit Yetim1, Ozcan Ozeke, Bulent Deveci, M Timur Selcuk, Dursun Aras.   

Abstract

Combined activated protein C resistance and dilated cardiomyopathy result in a multiplicative effect on thrombosis risk. However, it is not known that whether there is an association with activated protein C resistance and dilated cardiomyopathy. We present a 18-year-old patient with dilated cardiomyopathy, who exhibited multi-chamber intracardiac thrombi on transthoracic echocardiography associated with activated protein C resistance. Our cases emphasizes that patients with cardiac thrombosis before adulthood should be screened for an underlying coagulation abnormality besides underlying cardiac disorders.

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Year:  2005        PMID: 16378162     DOI: 10.1007/s10554-005-7437-4

Source DB:  PubMed          Journal:  Int J Cardiovasc Imaging        ISSN: 1569-5794            Impact factor:   2.357


  10 in total

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Journal:  Angiology       Date:  2003-01       Impact factor: 3.619

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Authors:  Paul M Ridker
Journal:  Clin Cornerstone       Date:  2002

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Authors:  J H Griffin; B Evatt; C Wideman; J A Fernández
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7.  Mutation in blood coagulation factor V associated with resistance to activated protein C.

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Journal:  Nature       Date:  1994-05-05       Impact factor: 49.962

8.  Prevalence of resistance against activated protein C resulting from factor V Leiden is significantly increased in myocardial infarction: investigation of 507 patients with myocardial infarction.

Authors:  Katharina Middendorf; Peter Göhring; Tanya Y Huehns; Dietrich Seidel; Gerhard Steinbeck; Sigrid Nikol
Journal:  Am Heart J       Date:  2004-05       Impact factor: 4.749

9.  Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.

Authors:  B Dahlbäck; M Carlsson; P J Svensson
Journal:  Proc Natl Acad Sci U S A       Date:  1993-02-01       Impact factor: 11.205

10.  Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study.

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Journal:  Lancet       Date:  1993 Dec 18-25       Impact factor: 79.321

  10 in total

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