Literature DB >> 16377722

Rifampin augments cytokine-induced nitric oxide production in human alveolar epithelial cells.

Yael Yuhas1, Eva Berent, Hila Ovadiah, Inbar Azoulay, Shai Ashkenazi.   

Abstract

Rifampin increased nitric oxide production and inducible nitric oxide synthase expression in alveolar cells stimulated with cytokines. Nitric oxide concentrations after induction with cytokines, cytokines with 10 microg/ml rifampin, and cytokines with 50 microg/ml rifampin were 3.2, 4.5, and 8.8 microM, respectively (P < 0.02 versus cytokines alone). This indicates that rifampin modulates the immune response.

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Year:  2006        PMID： 16377722      PMCID： PMC1346828          DOI： 10.1128/AAC.50.1.396-398.2006

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

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  13 in total

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