Literature DB >> 16377700

Pentamidine is active in a neutropenic murine model of acute invasive pulmonary fusariosis.

Michail S Lionakis1, Georgios Chamilos, Russell E Lewis, Nathan P Wiederhold, Issam I Raad, George Samonis, Dimitrios P Kontoyiannis.   

Abstract

We studied the efficacy of pentamidine (PNT) as prophylaxis or early treatment in acute pulmonary fusariosis in neutropenic mice. PNT-preexposed mice had significantly improved survival and reduced fungal burden compared to amphotericin B-preexposed and untreated mice. PNT-treated mice had increased survival but no difference in fungal burden versus untreated mice.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16377700      PMCID： PMC1346817          DOI： 10.1128/AAC.50.1.294-297.2006

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  In vitro and in vivo experimental activities of antifungal agents against Fusarium solani.

Authors:  J Guarro; I Pujol; E Mayayo
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

2.  Comparison of in vitro antifungal susceptibilities of conidia and hyphae of filamentous fungi.

Authors:  J Guarro; C Llop; C Aguilar; I Pujol
Journal:  Antimicrob Agents Chemother       Date:  1997-12       Impact factor: 5.191

3.  Lack of activity of amphotericin B in systemic murine fusarial infection.

Authors:  E J Anaissie; R Hachem; C Legrand; P Legenne; P Nelson; G P Bodey
Journal:  J Infect Dis       Date:  1992-06       Impact factor: 5.226

Review 4.  Pathogenesis I: interactions of host cells and fungi.

Authors:  K V Clemons; V L Calich; E Burger; S G Filler; M Grazziutti; J Murphy; E Roilides; A Campa; M R Dias; J E Edwards; Y Fu; G Fernandes-Bordignon; A Ibrahim; H Katsifa; C G Lamaignere; L H Meloni-Bruneri; J Rex; C A Savary; C Xidieh
Journal:  Med Mycol       Date:  2000       Impact factor: 4.076

5.  Pentamidine: clinical pharmacologic correlations in man and mice.

Authors:  T P Waalkes; C Denham; V T DeVita
Journal:  Clin Pharmacol Ther       Date:  1970 Jul-Aug       Impact factor: 6.875

6.  Itraconazole preexposure attenuates the efficacy of subsequent amphotericin B therapy in a murine model of acute invasive pulmonary aspergillosis.

Authors:  Russell E Lewis; Randall A Prince; Jingduan Chi; Dimitrios P Kontoyiannis
Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

7.  Use of a new bioassay to study pentamidine pharmacokinetics.

Authors:  E M Bernard; H J Donnelly; M P Maher; D Armstrong
Journal:  J Infect Dis       Date:  1985-10       Impact factor: 5.226

8.  Aerosolized pentamidine prophylaxis for Pneumocystis carinii pneumonia after allogeneic marrow transplantation.

Authors:  T K Marras; K Sanders; J H Lipton; H A Messner; J Conly; C K Chan
Journal:  Transpl Infect Dis       Date:  2002-06       Impact factor: 2.228

9.  Pentamidine is active in vitro against Fusarium species.

Authors:  Michail S Lionakis; Russell E Lewis; George Samonis; Dimitrios P Kontoyiannis
Journal:  Antimicrob Agents Chemother       Date:  2003-10       Impact factor: 5.191

10.  Outcome determinants of fusariosis in a tertiary care cancer center: the impact of neutrophil recovery.

Authors:  D P Kontoyiannis; G P Bodey; H Hanna; R Hachem; M Boktour; E Girgaway; M Mardani; I I Raad
Journal:  Leuk Lymphoma       Date:  2004-01
View more
  4 in total

1.  Mouse models for the study of fungal pneumonia: a collection of detailed experimental protocols for the study of Coccidioides, Cryptococcus, Fusarium, Histoplasma and combined infection due to Aspergillus-Rhizopus.

Authors:  Maged Muhammed; Marta Feldmesser; Lisa F Shubitz; Michail S Lionakis; Anita Sil; Yan Wang; Justin Glavis-Bloom; Russell E Lewis; John N Galgiani; Arturo Casadevall; Dimitrios P Kontoyiannis; Eleftherios Mylonakis
Journal:  Virulence       Date:  2012-05-01       Impact factor: 5.882

Review 2.  Therapeutic Challenges of Non-Aspergillus Invasive Mold Infections in Immunosuppressed Patients.

Authors:  Frederic Lamoth; Dimitrios P Kontoyiannis
Journal:  Antimicrob Agents Chemother       Date:  2019-10-22       Impact factor: 5.191

3.  Aspergillus tanneri sp. nov., a new pathogen that causes invasive disease refractory to antifungal therapy.

Authors:  Janyce A Sugui; Stephen W Peterson; Lily P Clark; Glenn Nardone; Les Folio; Gregory Riedlinger; Christa S Zerbe; Yvonne Shea; Christina M Henderson; Adrian M Zelazny; Steven M Holland; Kyung J Kwon-Chung
Journal:  J Clin Microbiol       Date:  2012-08-01       Impact factor: 5.948

Review 4.  Janus-Faced Molecules against Plant Pathogenic Fungi.

Authors:  Gaspar Banfalvi
Journal:  Int J Mol Sci       Date:  2021-11-15       Impact factor: 5.923
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.