Literature DB >> 16377561

Fanconi anemia (cross)linked to DNA repair.

Laura J Niedernhofer1, Astrid S Lalai, Jan H J Hoeijmakers.   

Abstract

Fanconi anemia is characterized by hypersensitivity to DNA interstrand crosslinks (ICLs) and susceptibility to tumor formation. Despite the identification of numerous Fanconi anemia (FANC) genes, the mechanism by which proteins encoded by these genes protect a cell from DNA interstrand crosslinks remains unclear. The recent discovery of two DNA helicases that, when defective, cause Fanconi anemia tips the balance in favor of the direct involvement of the FANC proteins in DNA repair and the bypass of DNA lesions.

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Year:  2005        PMID： 16377561     DOI： 10.1016/j.cell.2005.12.009

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  134 in total

Review 1.  Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.

Authors:  Blanka Sengerová; Anderson T Wang; Peter J McHugh
Journal:  Cell Cycle       Date:  2011-12-01       Impact factor: 4.534

2.  Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair.

Authors:  Justin Wai Chung Leung; Yucai Wang; Ka Wing Fong; Michael Shing Yan Huen; Lei Li; Junjie Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-06       Impact factor: 11.205

Review 3.  The Fanconi anemia pathway and DNA interstrand cross-link repair.

Authors:  Xiaoyu Su; Jun Huang
Journal:  Protein Cell       Date:  2011-09-23       Impact factor: 14.870

4.  CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.

Authors:  Jun Wang; Tapasree Roy Sarkar; Ming Zhou; Shikha Sharan; Daniel A Ritt; Timothy D Veenstra; Deborah K Morrison; A-Mei Huang; Esta Sterneck
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-30       Impact factor: 11.205

Review 5.  Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy.

Authors:  Angelo Guainazzi; Orlando D Schärer
Journal:  Cell Mol Life Sci       Date:  2010-08-21       Impact factor: 9.261

6.  Targeting the FANCJ-BRCA1 interaction promotes a switch from recombination to poleta-dependent bypass.

Authors:  J Xie; R Litman; S Wang; M Peng; S Guillemette; T Rooney; S B Cantor
Journal:  Oncogene       Date:  2010-02-22       Impact factor: 9.867

7.  The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks.

Authors:  Katsuhiro Hanada; Magda Budzowska; Mauro Modesti; Alex Maas; Claire Wyman; Jeroen Essers; Roland Kanaar
Journal:  EMBO J       Date:  2006-10-12       Impact factor: 11.598

8.  Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast.

Authors:  Nicole Cherng; Alexander A Shishkin; Lucas I Schlager; Ryan H Tuck; Laura Sloan; Robert Matera; Partha S Sarkar; Tetsuo Ashizawa; Catherine H Freudenreich; Sergei M Mirkin
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-31       Impact factor: 11.205

Review 9.  A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA cross-links derived from psoralen and abasic sites.

Authors:  Zhiyu Yang; Maryam Imani Nejad; Jacqueline Gamboa Varela; Nathan E Price; Yinsheng Wang; Kent S Gates
Journal:  DNA Repair (Amst)       Date:  2017-02-20

10.  Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links.

Authors:  Laura Zietlow; Leigh Anne Smith; Mika Bessho; Tadayoshi Bessho
Journal:  Biochemistry       Date:  2009-12-15       Impact factor: 3.162
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