Effect of the timing of tourniquet release on perioperative blood loss associated with cementless total knee arthroplasty: a prospective randomized study.

The control of perioperative blood loss is a major concern in cementless knee arthroplasty surgery. We randomized retrospectively 55 patients (60 knees in total) who had undergone cementless total knee arthroplasty and determined the efficacy of tourniquet release either "before" (30 knees) or "after" (30 knees) wound closure. Measurements of total blood loss showed significant differences between the groups ("Before" group, 906 +/- 238 mL; "After" group, 731 +/- 332 mL; P = .0225). The levels of red blood cells, hemoglobin, and hematocrit recovered to the preoperative levels by 3 months after surgery in both groups. In summary, we recommend that the tourniquet be released after wound closure and that a compressive dressing be applied with the aim of limiting or reducing perioperative blood loss without significant effects of the transfer requirement in the 2 groups, provided that tourniquet time is kept below 60 minutes to avoid ill effects of the tourniquet.

RCT Entities:   Population Interventions Outcomes