Literature DB >> 16374379

Large animal models: baboons for trauma, shock, and sepsis studies.

Heinz Redl1, Soheyl Bahrami.   

Abstract

A few limited examples of large animal models are outlined, with the main emphasis on baboon models. The baboon offers all the advantages of a large animal and is comparable with humans in nearly all physiological and immunological aspects. In addition, cross-reactivity with human therapeutic and diagnostic reagents allows testing of new species-specific therapies such as antihuman antibodies, on the one hand, and monitoring with available human analytical procedures, on the other.

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Year:  2005        PMID： 16374379     DOI： 10.1097/01.shk.0000191339.46777.63

Source DB:  PubMed          Journal:  Shock        ISSN： 1073-2322            Impact factor:   3.454


  9 in total

1.  Endotoxin-induced systemic inflammation activates microglia: [¹¹C]PBR28 positron emission tomography in nonhuman primates.

Authors:  Jonas Hannestad; Jean-Dominique Gallezot; Thomas Schafbauer; Keunpoong Lim; Tracy Kloczynski; Evan D Morris; Richard E Carson; Yu-Shin Ding; Kelly P Cosgrove
Journal:  Neuroimage       Date:  2012-07-06       Impact factor: 6.556

Review 2.  Intramedullary nailing as a 'second hit' phenomenon in experimental research: lessons learned and future directions.

Authors:  Nikolaos G Lasanianos; Nikolaos K Kanakaris; Peter V Giannoudis
Journal:  Clin Orthop Relat Res       Date:  2009-12-10       Impact factor: 4.176

Review 3.  OBESITY AND CRITICAL ILLNESS: INSIGHTS FROM ANIMAL MODELS.

Authors:  Peter N Mittwede; John S Clemmer; Patrick F Bergin; Lusha Xiang
Journal:  Shock       Date:  2016-04       Impact factor: 3.454

4.  Nonhuman primate model of polytraumatic hemorrhagic shock recapitulates early platelet dysfunction observed following severe injury in humans.

Authors:  Leasha J Schaub; Hunter B Moore; Andrew P Cap; Jacob J Glaser; Ernest E Moore; Forest R Sheppard
Journal:  J Trauma Acute Care Surg       Date:  2017-03       Impact factor: 3.313

5.  Indices of muscle and liver dysfunction after surviving hemorrhage and prolonged hypotension.

Authors:  Carmen Hinojosa-Laborde; Robert E Shade; Patrice A Frost; John W Dutton; Gary W Muniz; Ian L Hudson; Robert Carter; Kathy L Ryan
Journal:  J Trauma Acute Care Surg       Date:  2019-07       Impact factor: 3.313

6.  Assisted Reproductive Technologies (ART) with baboons generate live offspring: a nonhuman primate model for ART and reproductive sciences.

Authors:  Calvin R Simerly; Carlos A Castro; Ethan Jacoby; Kevin Grund; Janet Turpin; Dave McFarland; Jamie Champagne; Joe B Jimenez; Pat Frost; Cassondra Bauer; Laura Hewitson; Gerald Schatten
Journal:  Reprod Sci       Date:  2010-07-14       Impact factor: 3.060

Review 7.  Experimental trauma models: an update.

Authors:  Michael Frink; Hagen Andruszkow; Christian Zeckey; Christian Krettek; Frank Hildebrand
Journal:  J Biomed Biotechnol       Date:  2011-01-26

8.  Experimentally approaching the ICU: monitoring outcome-based responses in the two-hit mouse model of posttraumatic sepsis.

Authors:  Susanne Drechsler; Katrin M Weixelbaumer; Heinz Redl; Martijn van Griensven; Soheyl Bahrami; Marcin F Osuchowski
Journal:  J Biomed Biotechnol       Date:  2011-01-18

Review 9.  Nonhuman primate species as models of human bacterial sepsis.

Authors:  Lingye Chen; Karen E Welty-Wolf; Bryan D Kraft
Journal:  Lab Anim (NY)       Date:  2019-01-14       Impact factor: 12.625
  9 in total

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