Literature DB >> 1637338

A potentiometric titration study of the interaction of heparin with metal cations.

D Grant1, W F Long, F B Williamson.   

Abstract

Potentiometric titrations, at ionic strengths (I) ranging from 0.0057 to 0.336, suggest that Ca2+, Cu2+, Li+ and Na+ bind to heparin in a manner that depends on cation identity. These interactions were less affected by the value of I than those of heparin with Mg2+, which binds weakly below I0.050 and with K+, which binds weakly at I0.0057. Of the interactions studied, that of heparin with Cu2+ was the least readily reversible.

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Year:  1992        PMID： 1637338      PMCID： PMC1132812          DOI： 10.1042/bj2850477

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  13 in total

1.  The dependence on counter-cation of the degree of hydration of heparin.

Authors:  D Grant; W F Long; F B Williamson
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2.  Ion-exchange reactions between acid mucopolysaccharides and various cations.

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Authors:  R N Rej; K R Holme; A S Perlin
Journal:  Carbohydr Res       Date:  1990-10-25       Impact factor: 2.104

Review 4.  Angiogenic factors.

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5.  Binding of zinc ions to heparin. Analysis by equilibrium dialysis suggests the occurrence of two, entropy-driven, processes.

Authors:  N E Woodhead; W F Long; F B Williamson
Journal:  Biochem J       Date:  1986-07-01       Impact factor: 3.857

6.  Infrared spectroscopy of heparin-cation complexes.

Authors:  D Grant; W F Long; F B Williamson
Journal:  Biochem J       Date:  1987-05-15       Impact factor: 3.857

7.  The structure of water and its biological implications.

Authors:  J D Bernal
Journal:  Symp Soc Exp Biol       Date:  1965

8.  Infrared spectroscopy of heparins suggests that the region 750-950 cm-1 is sensitive to changes in iduronate residue ring conformation.

Authors:  D Grant; W F Long; C F Moffat; F B Williamson
Journal:  Biochem J       Date:  1991-04-01       Impact factor: 3.857

9.  A study of Ca(2+)-heparin complex-formation by polarimetry.

Authors:  D Grant; W F Long; C F Moffat; F B Williamson
Journal:  Biochem J       Date:  1992-03-01       Impact factor: 3.857

10.  Ceruloplasmin, copper ions, and angiogenesis.

Authors:  K S Raju; G Alessandri; M Ziche; P M Gullino
Journal:  J Natl Cancer Inst       Date:  1982-11       Impact factor: 13.506
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  3 in total

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2.  Salubrious effect of low molecular weight heparin on atherogenic diet-induced cardiac, hepatic and renal lipid peroxidation and collapse of antioxidant defences.

Authors:  P R Deepa; P Varalakshmi
Journal:  Mol Cell Biochem       Date:  2003-12       Impact factor: 3.396

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Authors:  T Tristan Brandhorst; René Roy; Marcel Wüthrich; Som Nanjappa; Hanna Filutowicz; Kevin Galles; Marco Tonelli; Darrell R McCaslin; Kenneth Satyshur; Bruce Klein
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  3 in total

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