Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Lisuride treatment of restless legs syndrome: first studies with monotherapy in de novo patients and in combination with levodopa in advanced disease.

Literature DB >> 16372146

Lisuride treatment of restless legs syndrome: first studies with monotherapy in de novo patients and in combination with levodopa in advanced disease.

H Benes¹, A Deissler, A Rodenbeck, A Engfer, R Kohnen.

Abstract

In two 4-week polysomnography pilot studies with 10 patients each, we investigated the efficacy of oral lisuride as monotherapy in de novo RLS patients as well as in combination with levodopa in advanced RLS. Daily doses at study end were 0.3 mg lisuride, plus 150 mg levodopa in the combination study. Marked improvements occurred in both studies in different PLM indexes and in the CGI. Levodopa dose could be decreased by 27%. Lisuride might be an efficacious treatment for RLS in general, and in combination with levodopa in advanced stage.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Levodopa
Lisuride

Year: 2006 PMID： 16372146 DOI： 10.1007/s00702-005-0386-1

Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN： 0300-9564 Impact factor: 3.575

10 in total

Review 1. Levodopa in the treatment of Parkinson's disease: current controversies.

Authors: C Warren Olanow; Yves Agid; Yoshi Mizuno; Alberto Albanese; Ubaldo Bonuccelli; U Bonucelli; Philip Damier; Justo De Yebenes; Oscar Gershanik; Mark Guttman; F Grandas; Mark Hallett; Ole Hornykiewicz; Peter Jenner; R Katzenschlager; William J Langston; Peter LeWitt; Eldad Melamed; M A Mena; P P Michel; Catherine Mytilineou; Jose A Obeso; Werner Poewe; Niall Quinn; R Raisman-Vozari; Ali H Rajput; Olivier Rascol; Christina Sampaio; Fabrizio Stocchi
Journal: Mov Disord Date: 2004-09 Impact factor: 10.338

2. Rapid onset of action of levodopa in restless legs syndrome: a double-blind, randomized, multicenter, crossover trial.

Authors: H Benes; B Kurella; J Kummer; J Kazenwadel; R Selzer; R Kohnen
Journal: Sleep Date: 1999-12-15 Impact factor: 5.849

3. Effective cabergoline treatment in idiopathic restless legs syndrome.

Authors: K Stiasny-Kolster; H Benes; I Peglau; M Hornyak; B Holinka; K Wessel; W Emser; M Leroux; R Kohnen; W H Oertel
Journal: Neurology Date: 2004-12-28 Impact factor: 9.910

Review 4. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health.

Authors: Richard P Allen; Daniel Picchietti; Wayne A Hening; Claudia Trenkwalder; Arthur S Walters; Jacques Montplaisi
Journal: Sleep Med Date: 2003-03 Impact factor: 3.492

5. Ropinirole is effective in the treatment of restless legs syndrome. TREAT RLS 2: a 12-week, double-blind, randomized, parallel-group, placebo-controlled study.

Authors: Arthur S Walters; William G Ondo; Tilman Dreykluft; Ron Grunstein; Daniel Lee; Kapil Sethi
Journal: Mov Disord Date: 2004-12 Impact factor: 10.338

6. Patch application of the dopamine agonist rotigotine to patients with moderate to advanced stages of restless legs syndrome: a double-blind, placebo-controlled pilot study.

Authors: Karin Stiasny-Kolster; Ralf Kohnen; Erwin Schollmayer; J Carsten Möller; Wolfgang H Oertel
Journal: Mov Disord Date: 2004-12 Impact factor: 10.338

7. Ropinirole decreases periodic leg movements and improves sleep parameters in patients with restless legs syndrome.

Authors: Richard Allen; Philip M Becker; Richard Bogan; Markus Schmidt; Clete A Kushida; June M Fry; J Steven Poceta; David Winslow
Journal: Sleep Date: 2004-08-01 Impact factor: 5.849

8. Long-term safety and efficacy of cabergoline for the treatment of idiopathic restless legs syndrome: results from an open-label 6-month clinical trial.

Authors: Heike Benes; Claus R Heinrich; Michael A Ueberall; Ralf Kohnen
Journal: Sleep Date: 2004-06-15 Impact factor: 5.849

9. Ropinirole in the treatment of restless legs syndrome: results from the TREAT RLS 1 study, a 12 week, randomised, placebo controlled study in 10 European countries.

Authors: C Trenkwalder; D Garcia-Borreguero; P Montagna; E Lainey; A W de Weerd; P Tidswell; G Saletu-Zyhlarz; W Telstad; L Ferini-Strambi
Journal: J Neurol Neurosurg Psychiatry Date: 2004-01 Impact factor: 10.154

Review 10. An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder.

Authors: Wayne A Hening; Richard P Allen; Christopher J Earley; Daniel L Picchietti; Michael H Silber
Journal: Sleep Date: 2004-05-01 Impact factor: 5.849

10 in total

7 in total

Review 1. The treatment of restless legs syndrome and periodic limb movement disorder in adults--an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses: an American Academy of Sleep Medicine Clinical Practice Guideline.

Authors: R Nisha Aurora; David A Kristo; Sabin R Bista; James A Rowley; Rochelle S Zak; Kenneth R Casey; Carin I Lamm; Sharon L Tracy; Richard S Rosenberg
Journal: Sleep Date: 2012-08-01 Impact factor: 5.849

2. Lisuride reduces involuntary periodic leg movements in spinocerebellar ataxia type 2 patients.

Authors: Luis Velázquez-Pérez; Roberto Rodríguez-Labrada; Lázaro Álvarez-González; Raúl Aguilera-Rodríguez; Mario Álvarez Sánchez; Nalia Canales-Ochoa; Lourdes Galicia Polo; Reyes Haro-Valencia; Jacqueline Medrano-Montero; Yaimeé Vázquez-Mojena; Arnoy Peña-Acosta; Annelié Estupiñán-Rodríguez; Noemí Rodríguez Pupo
Journal: Cerebellum Date: 2012-12 Impact factor: 3.847