Literature DB >> 16371775

Clinical profile and early surgical complications in the Cornea Donor Study.

Mark J Mannis1, Edward J Holland, Roy W Beck, Michael W Belin, Marc A Goldberg, Robin L Gal, Andrea D Kalajian, Kenneth R Kenyon, Craig Kollman, Katrina J Ruedy, Patricia Smith, Joel Sugar, Walter J Stark.   

Abstract

PURPOSE: The Cornea Donor Study was designed to investigate the safety and efficacy of older donor corneal tissue compared with younger donor tissue in recipient eyes at moderate risk to the graft from progressive endothelial failure. Baseline patient data, including indications for transplant, intraoperative complication rates, and early postoperative complication rates are described herein.
METHODS: This study was a multicenter prospective, double-masked, controlled clinical trial.
RESULTS: Fuchs dystrophy was the most common indication for corneal transplantation (61%). Intraoperative complications occurred in 33 (3%) patients. A persistent epithelial defect was the most commonly reported postoperative complication, occurring in 92 patients (8%).
CONCLUSION: Intraoperative and postoperative complication rates were low. There was no apparent association between donor or recipient age and either intraoperative or early postoperative complication rates.

Entities:  

Mesh：

Year:  2006        PMID： 16371775     DOI： 10.1097/01.ico.0000164832.69668.4b

Source DB:  PubMed          Journal:  Cornea        ISSN： 0277-3740            Impact factor:   2.651


  24 in total

1.  The effect of ABO blood incompatibility on corneal transplant failure in conditions with low-risk of graft rejection.

Authors:  Steven P Dunn; Walter J Stark; R Doyle Stulting; Jonathan H Lass; Alan Sugar; Mark A Pavilack; Patricia W Smith; Jean Paul Tanner; Mariya Dontchev; Robin L Gal; Roy W Beck; Craig Kollman; Mark J Mannis; Edward J Holland
Journal:  Am J Ophthalmol       Date:  2008-12-04       Impact factor: 5.258

2.  Mutations in AGBL1 cause dominant late-onset Fuchs corneal dystrophy and alter protein-protein interaction with TCF4.

Authors:  S Amer Riazuddin; Shivakumar Vasanth; Nicholas Katsanis; John D Gottsch
Journal:  Am J Hum Genet       Date:  2013-10-03       Impact factor: 11.025

3.  The effect of donor diabetes history on graft failure and endothelial cell density 10 years after penetrating keratoplasty.

Authors:  Jonathan H Lass; Tonya D Riddlesworth; Robin L Gal; Craig Kollman; Beth A Benetz; Francis W Price; Alan Sugar; Mark A Terry; Mark Soper; Roy W Beck
Journal:  Ophthalmology       Date:  2014-11-15       Impact factor: 12.079

4.  Intraocular pressure after descemet stripping endothelial keratoplasty (DSEK).

Authors:  Carla P Nieuwendaal; Ivanka J E van der Meulen; Ruth Lapid-Gortzak; Maarten P Mourits
Journal:  Int Ophthalmol       Date:  2012-11-06       Impact factor: 2.031

5.  Corneal graft rejection 10 years after penetrating keratoplasty in the cornea donor study.

Authors:  Steven P Dunn; Robin L Gal; Craig Kollman; Dan Raghinaru; Mariya Dontchev; Christopher L Blanton; Edward J Holland; Jonathan H Lass; Kenneth R Kenyon; Mark J Mannis; Shahzad I Mian; Christopher J Rapuano; Walter J Stark; Roy W Beck
Journal:  Cornea       Date:  2014-10       Impact factor: 2.651

6.  Mutations in LOXHD1, a recessive-deafness locus, cause dominant late-onset Fuchs corneal dystrophy.

Authors:  S Amer Riazuddin; David S Parker; Elyse J McGlumphy; Edwin C Oh; Benjamin W Iliff; Thore Schmedt; Ula Jurkunas; Robert Schleif; Nicholas Katsanis; John D Gottsch
Journal:  Am J Hum Genet       Date:  2012-02-16       Impact factor: 11.025

7.  Age-severity relationships in families linked to FCD2 with retroillumination photography.

Authors:  Elyse J McGlumphy; William S Yeo; S Amer Riazuddin; Amr Al-Saif; Jiangxia Wang; Allen O Eghrari; Danielle N Meadows; David G Emmert; Nicholas Katsanis; John D Gottsch
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-09-01       Impact factor: 4.799

8.  The effect of donor age on corneal transplantation outcome results of the cornea donor study.

Authors:  Robin L gal; Mariya Dontchev; Roy W Beck; Mark J Mannis; Edward J Holland; Craig Kollman; Steven P Dunn; Ellen L Heck; Jonathan H Lass; Monty M Montoya; Robert L Schultze; R Doyle Stulting; Alan Sugar; Joel Sugar; Bradley Tennant; David D Verdier
Journal:  Ophthalmology       Date:  2008-04       Impact factor: 12.079

9.  Donor age and corneal endothelial cell loss 5 years after successful corneal transplantation. Specular microscopy ancillary study results.

Authors:  Jonathan H Lass; Robin L Gal; Mariya Dontchev; Roy W Beck; Craig Kollman; Steven P Dunn; Ellen Heck; Edward J Holland; Mark J Mannis; Monty M Montoya; Robert L Schultze; R Doyle Stulting; Alan Sugar; Joel Sugar; Bradley Tennant; David D Verdier
Journal:  Ophthalmology       Date:  2008-04       Impact factor: 12.079

10.  Recipient risk factors for graft failure in the cornea donor study.

Authors:  Alan Sugar; Jean Paul Tanner; Mariya Dontchev; Brad Tennant; Robert L Schultze; Steven P Dunn; Thomas D Lindquist; Robin L Gal; Roy W Beck; Craig Kollman; Mark J Mannis; Edward J Holland
Journal:  Ophthalmology       Date:  2009-04-23       Impact factor: 12.079
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