Literature DB >> 16371391

Umbilical cord blood procalcitonin and C reactive protein concentrations as markers for early diagnosis of very early onset neonatal infection.

N Joram1, C Boscher, S Denizot, V Loubersac, N Winer, J C Roze, C Gras-Le Guen.   

Abstract

Procalcitonin (PCT) and C reactive protein (CRP) concentrations in umbilical cord blood of 197 neonates were measured to evaluate their value as markers of infection. Sixteen of the neonates were infected. The sensitivity, specificity, and negative and positive predictive values were respectively 87.5%, 98.7%, 87.5%, and 98.7% for PCT and 50%, 97%, 67%, and 94% for CRP. Serum PCT in cord blood seems to be a useful and early marker of antenatal infection.

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Year:  2006        PMID： 16371391      PMCID： PMC2672656          DOI： 10.1136/adc.2005.074245

Source DB:  PubMed          Journal:  Arch Dis Child Fetal Neonatal Ed        ISSN： 1359-2998            Impact factor:   5.747


  5 in total

1.  Increased serum procalcitonin in newborn infants without infection.

Authors:  C Sachse; F Dressler; E Henkel
Journal:  Clin Chem       Date:  1998-06       Impact factor: 8.327

2.  Lack of specificity of procalcitonin for sepsis diagnosis in premature infants.

Authors:  A Lapillonne; E Basson; G Monneret; J Bienvenu; B L Salle
Journal:  Lancet       Date:  1998-04-18       Impact factor: 79.321

3.  Procalcitonin as a marker for the early diagnosis of neonatal infection.

Authors:  D Gendrel; M Assicot; J Raymond; F Moulin; C Francoual; J Badoual; C Bohuon
Journal:  J Pediatr       Date:  1996-04       Impact factor: 4.406

4.  Reliability of procalcitonin concentrations for the diagnosis of sepsis in critically ill neonates.

Authors:  C Chiesa; A Panero; N Rossi; M Stegagno; M De Giusti; J F Osborn; L Pacifico
Journal:  Clin Infect Dis       Date:  1998-03       Impact factor: 9.079

5.  Diagnostic audit of C-reactive protein in neonatal infection.

Authors:  N J Mathers; F Pohlandt
Journal:  Eur J Pediatr       Date:  1987-03       Impact factor: 3.183
  5 in total
  17 in total

Review 1.  Inflammatory markers in cord blood or maternal serum for early detection of neonatal sepsis-a systemic review and meta-analysis.

Authors:  H Su; S-S Chang; C-M Han; K-Y Wu; M-C Li; C-Y Huang; C-L Lee; J-Y Wu; C-C Lee
Journal:  J Perinatol       Date:  2014-01-23       Impact factor: 2.521

2.  Normal Ranges for Acute Phase Reactants (Interleukin-6, Tumour Necrosis Factor-alpha and C-reactive Protein) in Umbilical Cord Blood of Healthy Term Neonates at the Mount Hope Women's Hospital, Trinidad.

Authors:  A Khan; Z Ali
Journal:  West Indian Med J       Date:  2014-06-11       Impact factor: 0.171

3.  Clinical chorioamnionitis at term VI: acute chorioamnionitis and funisitis according to the presence or absence of microorganisms and inflammation in the amniotic cavity.

Authors:  Roberto Romero; Piya Chaemsaithong; Nikolina Docheva; Steven J Korzeniewski; Juan P Kusanovic; Bo Hyun Yoon; Jung-Sun Kim; Noppadol Chaiyasit; Ahmed I Ahmed; Faisal Qureshi; Suzanne M Jacques; Chong Jai Kim; Sonia S Hassan; Tinnakorn Chaiworapongsa; Lami Yeo; Yeon Mee Kim
Journal:  J Perinat Med       Date:  2016-01       Impact factor: 1.901

4.  Umbilical cord blood procalcitonin level in early neonatal infections: a 4-year university hospital cohort study.

Authors:  N Joram; J-B Muller; S Denizot; J-L Orsonneau; J Caillon; J-C Rozé; C Gras-Le Guen
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-02-12       Impact factor: 3.267

5.  Maternal serum ferritin concentration is positively associated with newborn iron stores in women with low ferritin status in late pregnancy.

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6.  A new procalcitonin cord-based algorithm in early-onset neonatal infection: for a change of paradigm.

Authors:  S Lencot; B Cabaret; G Sauvage; C Laurans; E Launay; J-L Orsonneau; J Caillon; C Boscher; J-C Roze; C Gras-Le Guen
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-02-11       Impact factor: 3.267

Review 7.  Umbilical blood biomarkers for predicting early-onset neonatal sepsis.

Authors:  Ying Fan; Jia-Lin Yu
Journal:  World J Pediatr       Date:  2012-05-10       Impact factor: 2.764

8.  Inflammation-related epigenetic risk and child and adolescent mental health: A prospective study from pregnancy to middle adolescence.

Authors:  Edward D Barker; Charlotte A M Cecil; Esther Walton; Lotte C Houtepen; Thomas G O'Connor; Andrea Danese; Sara R Jaffee; Sarah K G Jensen; Carmine Pariante; Wendy McArdle; Tom R Gaunt; Caroline L Relton; Susanna Roberts
Journal:  Dev Psychopathol       Date:  2018-08

9.  Procalcitonin in Preterm Neonates: A Different Threshold and Prolonged Interpretation.

Authors:  Blandine Bianco; Bérengère François-Garret; Marine Butin; Cyril Dalmasso; Florence Casagrande; Mostafa Mokhtari; Sergio Eleni Dit Trolli
Journal:  Front Pediatr       Date:  2021-05-17       Impact factor: 3.418

10.  Biomarkers for diagnosis of neonatal infections: A systematic analysis of their potential as a point-of-care diagnostics.

Authors:  Mahbuba Meem; Joyanta K Modak; Roman Mortuza; Mahboob Morshed; Mohammad Shahidul Islam; Samir K Saha
Journal:  J Glob Health       Date:  2011-12       Impact factor: 4.413
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