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Literature DB >> 16370017

The fluorinase from Streptomyces cattleya is also a chlorinase.

Hai Deng¹, Steven L Cobb, Andrew R McEwan, Ryan P McGlinchey, James H Naismith, David O'Hagan, David A Robinson, Jonathan B Spencer.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2006 PMID： 16370017 PMCID： PMC3314195 DOI： 10.1002/anie.200503582

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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17 in total

1. Identification of a PLP-Dependent Threonine Transaldolase: A Novel Enzyme Involved in 4-Fluorothreonine Biosynthesis in Streptomyces cattleya This work was supported by the Biotechnological and Biological Sciences Research Council and the University of St Andrews.

Authors: Cormac D. Murphy; David O'Hagan; Christoph Schaffrath
Journal: Angew Chem Int Ed Engl Date: 2001-12-03 Impact factor: 15.336

Review 2. The fluorinated natural products.

Authors: D B Harper; D O'Hagan
Journal: Nat Prod Rep Date: 1994-04 Impact factor: 13.423

3. Expression of Batis maritima methyl chloride transferase in Escherichia coli.

Authors: X Ni; L P Hager
Journal: Proc Natl Acad Sci U S A Date: 1999-03-30 Impact factor: 11.205

4. Isolation of an aldehyde dehydrogenase involved in the oxidation of fluoroacetaldehyde to fluoroacetate in Streptomyces cattleya.

Authors: C D Murphy; S J Moss; D O'Hagan
Journal: Appl Environ Microbiol Date: 2001-10 Impact factor: 4.792

5. Insight into enzymatic C-F bond formation from QM and QM/MM calculations.

Authors: Hans Martin Senn; David O'Hagan; Walter Thiel
Journal: J Am Chem Soc Date: 2005-10-05 Impact factor: 15.419

6. Isolation and characterisation of 5'-fluorodeoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya.

Authors: Christoph Schaffrath; Hai Deng; David O'Hagan
Journal: FEBS Lett Date: 2003-07-17 Impact factor: 4.124

7. Identification of 5-fluoro-5-deoxy-D-ribose-1-phosphate as an intermediate in fluorometabolite biosynthesis in Streptomyces cattleya.

Authors: Steven L Cobb; Hai Deng; John T G Hamilton; Ryan P McGlinchey; David O'Hagan
Journal: Chem Commun (Camb) Date: 2004-02-03 Impact factor: 6.222

8. Biochemical characterization of chloromethane emission from the wood-rotting fungus phellinus pomaceus

Authors:
Journal: Appl Environ Microbiol Date: 1998-08 Impact factor: 4.792

9. Crystal structure and mechanism of a bacterial fluorinating enzyme.

Authors: Changjiang Dong; Fanglu Huang; Hai Deng; Christoph Schaffrath; Jonathan B Spencer; David O'Hagan; James H Naismith
Journal: Nature Date: 2004-02-05 Impact factor: 49.962

10. Enzymatic fluorination in Streptomyces cattleya takes place with an inversion of configuration consistent with an SN2 reaction mechanism.

Authors: Cosimo D Cadicamo; Jacques Courtieu; Hai Deng; Abdelkrim Meddour; David O'Hagan
Journal: Chembiochem Date: 2004-05-03 Impact factor: 3.164

24 in total

10. Preparation, Assay, and Application of Chlorinase SalL for the Chemoenzymatic Synthesis of S-Adenosyl-l-Methionine and Analogs.

Authors: Tony D Davis; Sylvia Kunakom; Michael D Burkart; Alessandra S Eustaquio
Journal: Methods Enzymol Date: 2018-04-02 Impact factor: 1.600

The fluorinase from Streptomyces cattleya is also a chlorinase.

1. Identification of a PLP-Dependent Threonine Transaldolase: A Novel Enzyme Involved in 4-Fluorothreonine Biosynthesis in Streptomyces cattleya This work was supported by the Biotechnological and Biological Sciences Research Council and the University of St Andrews.

Review 2. The fluorinated natural products.

3. Expression of Batis maritima methyl chloride transferase in Escherichia coli.

4. Isolation of an aldehyde dehydrogenase involved in the oxidation of fluoroacetaldehyde to fluoroacetate in Streptomyces cattleya.

5. Insight into enzymatic C-F bond formation from QM and QM/MM calculations.

6. Isolation and characterisation of 5'-fluorodeoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya.

7. Identification of 5-fluoro-5-deoxy-D-ribose-1-phosphate as an intermediate in fluorometabolite biosynthesis in Streptomyces cattleya.

8. Biochemical characterization of chloromethane emission from the wood-rotting fungus phellinus pomaceus

9. Crystal structure and mechanism of a bacterial fluorinating enzyme.

10. Enzymatic fluorination in Streptomyces cattleya takes place with an inversion of configuration consistent with an SN2 reaction mechanism.

Review 1. Halogenase engineering and its utility in medicinal chemistry.

Review 2. What's new in enzymatic halogenations.

Review 3. Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.

4. Halomethane biosynthesis: structure of a SAM-dependent halide methyltransferase from Arabidopsis thaliana.

5. Mechanism of enzymatic fluorination in Streptomyces cattleya.

6. Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide.

Review 7. Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives.

Review 8. AdoMet analog synthesis and utilization: current state of the art.

9. Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogs.

10. Preparation, Assay, and Application of Chlorinase SalL for the Chemoenzymatic Synthesis of S-Adenosyl-l-Methionine and Analogs.