Literature DB >> 16369813

Evaluation of the effect of multiple-dose administration of R411, a dual alpha4beta1-alpha4beta7 integrin antagonist on the major CYP isoform activities in healthy volunteers.

Youssef Hijazi, Horst Welker, Albert E Dorr, Karl Frank, Louis M Renzetti, Indravadan Patel.   

Abstract

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Year:  2005        PMID： 16369813     DOI： 10.1007/s00228-005-0067-x

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


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  8 in total

1.  Pharmacokinetics, safety, and tolerability of R411, a dual alpha4beta1-alpha4beta7 integrin antagonist after oral administration at single and multiple once-daily ascending doses in healthy volunteers.

Authors:  Youssef Hijazi; Horst Welker; Albert E Dorr; Jian-Ping Tang; Roger Blain; Louis M Renzetti; Richat Abbas
Journal:  J Clin Pharmacol       Date:  2004-12       Impact factor: 3.126

2.  A rapid, specific, and sensitive method for the determination of acetylation phenotype using dapsone.

Authors:  R H Queiroz; S A Dreossi; D Carvalho
Journal:  J Anal Toxicol       Date:  1997 May-Jun       Impact factor: 3.367

3.  Determination of chlorzoxazone and 6-hydroxychlorzoxazone in human plasma and urine by high-performance liquid chromatography.

Authors:  R F Frye; D D Stiff
Journal:  J Chromatogr B Biomed Appl       Date:  1996-11-15

4.  Separation and quantitation of debrisoquine and 4-hydroxydebrisoquine in human urine by capillary electrophoresis and high-performance liquid chromatography.

Authors:  A Cifuentes; J Valencia; E Sanz; M J Sánchez; M A Rodríguez-Delgado
Journal:  J Chromatogr A       Date:  1997-08-22       Impact factor: 4.759

5.  Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes.

Authors:  R F Frye; G R Matzke; A Adedoyin; J A Porter; R A Branch
Journal:  Clin Pharmacol Ther       Date:  1997-10       Impact factor: 6.875

6.  Comparison of the metabolism and toxicity of dapsone in rat, mouse and man.

Authors:  M D Tingle; R Mahmud; J L Maggs; M Pirmohamed; B K Park
Journal:  J Pharmacol Exp Ther       Date:  1997-11       Impact factor: 4.030

7.  Validation of a high-performance liquid chromatography assay for quantification of caffeine and paraxanthine in human serum in the context of CYP1A2 phenotyping.

Authors:  J P Koch; G W ten Tusscher; J G Koppe; H J Guchelaar
Journal:  Biomed Chromatogr       Date:  1999-06       Impact factor: 1.902

8.  S-mephenytoin hydroxylation phenotypes in a Jordanian population.

Authors:  H F Hadidi; Y M Irshaid; R L Woosley; J R Idle; D A Flockhart
Journal:  Clin Pharmacol Ther       Date:  1995-11       Impact factor: 6.875
  8 in total
  1 in total

Review 1.  Role of integrin alpha4 in drug resistance of leukemia.

Authors:  Stephanie Shishido; Halvard Bönig; Yong-Mi Kim
Journal:  Front Oncol       Date:  2014-05-23       Impact factor: 6.244
  1 in total

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