Literature DB >> 16369047

Regulation of voltage-gated Ca2+ channels by calmodulin.

D Brent Halling1, Paula Aracena-Parks, Susan L Hamilton.   

Abstract

Calmodulin, a highly versatile and ubiquitously expressed Ca2+ sensor, regulates the function of many enzymes and ion channels. Both Ca2+-dependent inactivation and Ca2+-dependent facilitation of the voltage-gated Ca2+ channels Cav1.2 and Cav2.1 are regulated through an interaction with Ca2+-bound calmodulin. This review addresses the functional regulation of Cav1.2 and Cav2.1 by calmodulin and discusses how Ca2+ binding to a single calmodulin molecule can regulate opposing functions of the voltage-gated Ca2+ channels.

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Year:  2005        PMID： 16369047     DOI： 10.1126/stke.3152005re15

Source DB:  PubMed          Journal:  Sci STKE        ISSN： 1525-8882


  30 in total

Review 1.  Trafficking and stability of voltage-gated calcium channels.

Authors:  Brett A Simms; Gerald W Zamponi
Journal:  Cell Mol Life Sci       Date:  2011-10-02       Impact factor: 9.261

2.  Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.

Authors:  Katrin Domes; Jie Ding; Toni Lemke; Anne Blaich; Jörg W Wegener; Julia Brandmayr; Sven Moosmang; Franz Hofmann
Journal:  J Biol Chem       Date:  2011-08-05       Impact factor: 5.157

3.  Thermodynamic linkage between calmodulin domains binding calcium and contiguous sites in the C-terminal tail of Ca(V)1.2.

Authors:  T Idil Apak Evans; Johannes W Hell; Madeline A Shea
Journal:  Biophys Chem       Date:  2011-06-24       Impact factor: 2.352

4.  Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)beta subunits.

Authors:  Arippa Ravindran; Qi Zong Lao; Jo Beth Harry; Parwiz Abrahimi; Evgeny Kobrinsky; Nikolai M Soldatov
Journal:  Proc Natl Acad Sci U S A       Date:  2008-06-05       Impact factor: 11.205

5.  Facilitation of murine cardiac L-type Ca(v)1.2 channel is modulated by calmodulin kinase II-dependent phosphorylation of S1512 and S1570.

Authors:  Anne Blaich; Andrea Welling; Stefanie Fischer; Jörg Werner Wegener; Katharina Köstner; Franz Hofmann; Sven Moosmang
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-17       Impact factor: 11.205

6.  Label-free detection of protein-protein interactions using a calmodulin-modified nanowire transistor.

Authors:  Tsung-Wu Lin; Po-Jen Hsieh; Chih-Lung Lin; Yi-Ya Fang; Jia-Xun Yang; Chia-Chang Tsai; Pei-Ling Chiang; Chien-Yuan Pan; Yit-Tsong Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-23       Impact factor: 11.205

Review 7.  Calcium channels and short-term synaptic plasticity.

Authors:  William A Catterall; Karina Leal; Evanthia Nanou
Journal:  J Biol Chem       Date:  2013-02-11       Impact factor: 5.157

Review 8.  L-type calcium channel targeting and local signalling in cardiac myocytes.

Authors:  Robin M Shaw; Henry M Colecraft
Journal:  Cardiovasc Res       Date:  2013-02-14       Impact factor: 10.787

9.  Calmodulin mutations associated with recurrent cardiac arrest in infants.

Authors:  Lia Crotti; Christopher N Johnson; Elisabeth Graf; Gaetano M De Ferrari; Bettina F Cuneo; Marc Ovadia; John Papagiannis; Michael D Feldkamp; Subodh G Rathi; Jennifer D Kunic; Matteo Pedrazzini; Thomas Wieland; Peter Lichtner; Britt-Maria Beckmann; Travis Clark; Christian Shaffer; D Woodrow Benson; Stefan Kääb; Thomas Meitinger; Tim M Strom; Walter J Chazin; Peter J Schwartz; Alfred L George
Journal:  Circulation       Date:  2013-02-06       Impact factor: 29.690

10.  The kinetics of Ca(2+)-dependent switching in a calmodulin-IQ domain complex.

Authors:  D J Black; J Eva Selfridge; Anthony Persechini
Journal:  Biochemistry       Date:  2007-10-24       Impact factor: 3.162
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