Literature DB >> 16368805

The safety and efficacy of spinal anesthesia for surgery in infants: the Vermont Infant Spinal Registry.

Robert K Williams1, David C Adams, Eva V Aladjem, Joseph M Kreutz, Kennith H Sartorelli, Dennis W Vane, J Christian Abajian.   

Abstract

Studies with modest numbers of patients have suggested that spinal anesthesia in infants is associated with a very infrequent incidence of complications, such as hypoxemia, bradycardia, and postoperative apnea. Although spinal anesthesia would seem to be a logical alternative to general anesthesia for many surgical procedures, it remains an underutilized technique. Since 1978, clinical data concerning all infants undergoing spinal anesthesia at the University of Vermont have been prospectively recorded. In all, 1554 patients have been studied. Anesthesia was performed by anesthesia trainees and attending anesthesiologists. The success rate for LP was 97.4%. An adequate level of spinal anesthesia was achieved in 95.4% of cases. The average time required to induce spinal anesthesia was 10 min. Oxygen hemoglobin desaturation to <90% was observed in 10 patients. Bradycardia (heart rate <100 bpm) occurred in 24 patients (1.6%). This study confirms the infrequent incidence of complications associated with spinal anesthesia in infants. Spinal anesthesia can be performed safely, efficiently, and with the expectation of a high degree of success. Spinal anesthesia should be strongly considered as an alternative to general anesthesia for lower abdominal and lower extremity surgery in infants.

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Year:  2006        PMID: 16368805     DOI: 10.1213/01.ANE.0000159162.86033.21

Source DB:  PubMed          Journal:  Anesth Analg        ISSN: 0003-2999            Impact factor:   5.108


  23 in total

1.  Predictors of Failure of Awake Regional Anesthesia for Neonatal Hernia Repair: Data from the General Anesthesia Compared to Spinal Anesthesia Study--Comparing Apnea and Neurodevelopmental Outcomes.

Authors:  Geoff Frawley; Graham Bell; Nicola Disma; Davinia E Withington; Jurgen C de Graaff; Neil S Morton; Mary Ellen McCann; Sarah J Arnup; Oliver Bagshaw; Andrea Wolfler; David Bellinger; Andrew J Davidson
Journal:  Anesthesiology       Date:  2015-07       Impact factor: 7.892

2.  Validation of a preclinical spinal safety model: effects of intrathecal morphine in the neonatal rat.

Authors:  B David Westin; Suellen M Walker; Ronald Deumens; Marjorie Grafe; Tony L Yaksh
Journal:  Anesthesiology       Date:  2010-07       Impact factor: 7.892

3.  Neuroprotective properties of vitamin C on equipotent anesthetic concentrations of desflurane, isoflurane, or sevoflurane in high fat diet fed neonatal mice.

Authors:  Kai-Xiang Xu; Jun Tao; Nan Zhang; Jian-Zhong Wang
Journal:  Int J Clin Exp Med       Date:  2015-07-15

4.  Spinal anesthesia for surgery longer than 60 min in infants: experience from the first 2 years of a spinal anesthesia program.

Authors:  Mehdi Trifa; Dmitry Tumin; Emmett E Whitaker; Tarun Bhalla; Venkata R Jayanthi; Joseph D Tobias
Journal:  J Anesth       Date:  2018-05-28       Impact factor: 2.078

5.  Spinal anesthesia in a child with Brachmann-de Lange (Cornelia de Lange) syndrome.

Authors:  Ludmyla Kachko; Elena Sanko; Enrique Freud; Jacob Katz
Journal:  J Anesth       Date:  2010-10-28       Impact factor: 2.078

6.  Despite differences in cytosolic calcium regulation, lidocaine toxicity is similar in adult and neonatal rat dorsal root ganglia in vitro.

Authors:  Lisa V Doan; Olga Eydlin; Boris Piskoun; Richard P Kline; Esperanza Recio-Pinto; Andrew D Rosenberg; Thomas J J Blanck; Fang Xu
Journal:  Anesthesiology       Date:  2014-01       Impact factor: 7.892

7.  Combined lumbar spinal and thoracic high-epidural regional anesthesia as an alternative to general anesthesia for high-risk patients undergoing gastrointestinal and colorectal surgery.

Authors:  James Skipworth; Attavar Srilekha; Dimitri Raptis; David O'Callaghan; Siri Siriwardhana; Romi Navaratnam
Journal:  World J Surg       Date:  2009-09       Impact factor: 3.352

8.  Combined spinal epidural anaesthesia for gastroschisis repair.

Authors:  Mangesh Gore; Kunal Joshi; Nandini Dave
Journal:  Indian J Anaesth       Date:  2009-04

9.  Adverse Events and Resource Utilization After Spinal and General Anesthesia in Infants Undergoing Pyloromyotomy.

Authors:  Caleb Ing; Lena S Sun; Alexander F Friend; Arthur Roh; Susan Lei; Howard Andrews; Guohua Li; Robert K Williams
Journal:  Reg Anesth Pain Med       Date:  2016 Jul-Aug       Impact factor: 6.288

10.  Evaluation of spinal toxicity and long-term spinal reflex function after intrathecal levobupivaciane in the neonatal rat.

Authors:  Emre Hamurtekin; Bethany L Fitzsimmons; Veronica I Shubayev; Marjorie R Grafe; Ronald Deumens; Tony L Yaksh; Suellen M Walker
Journal:  Anesthesiology       Date:  2013-07       Impact factor: 7.892

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