Literature DB >> 16368279

The effects of local platelet rich plasma delivery on diabetic fracture healing.

Ankur Gandhi1, Christopher Doumas, Christopher Dumas, J Patrick O'Connor, J Russell Parsons, Sheldon S Lin.   

Abstract

Several studies have documented that diabetes impairs bone healing clinically and experimentally. The percutaneous delivery of platelet rich plasma (PRP) was used in the diabetic BB Wistar femur fracture model to investigate the use of PRP as a concentrated source of critical early growth factors on bone healing. PRP delivery at the fracture site normalized the early (cellular proliferation and chondrogenesis) parameters while improving the late (mechanical strength) parameters of diabetic fracture healing. These results suggest a role for PRP in mediating diabetic fracture healing and potentially other high risk fractures.

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Year:  2005        PMID： 16368279     DOI： 10.1016/j.bone.2005.10.019

Source DB:  PubMed          Journal:  Bone        ISSN： 1873-2763            Impact factor:   4.398


  36 in total

1.  The use of autologous blood-derived growth factors in bone regeneration.

Authors:  Roberto Civinini; Armando Macera; Lorenzo Nistri; Birgit Redl; Massimo Innocenti
Journal:  Clin Cases Miner Bone Metab       Date:  2011-01

Review 2.  Platelet-rich plasma and platelet gel: a review.

Authors:  Peter A M Everts; Johannes T A Knape; Gernot Weibrich; Jacques P A M Schönberger; Johannes Hoffmann; Eddy P Overdevest; Henk A M Box; André van Zundert
Journal:  J Extra Corpor Technol       Date:  2006-06

3.  Autologous platelet gel and fibrin sealant enhance the efficacy of total knee arthroplasty: improved range of motion, decreased length of stay and a reduced incidence of arthrofibrosis.

Authors:  Peter A M Everts; Roger J J Devilee; Cornelis J M Oosterbos; Christine Brown Mahoney; Maarten Eeftinck Schattenkerk; Johannes T A Knape; André van Zundert
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2007-02-24       Impact factor: 4.342

Review 4.  The use of autologous platelet-leukocyte gels to enhance the healing process in surgery, a review.

Authors:  P A Everts; E P Overdevest; J J Jakimowicz; C J Oosterbos; J P Schönberger; J T Knape; A van Zundert
Journal:  Surg Endosc       Date:  2007-04-13       Impact factor: 4.584

5.  The role of platelet-rich plasma in inducing musculoskeletal tissue healing.

Authors:  Brian C Halpern; Salma Chaudhury; Scott A Rodeo
Journal:  HSS J       Date:  2012-01-18

Review 6.  Background and rationale of platelet gel in orthopaedic surgery.

Authors:  Elisabetta Cenni; Lucia Savarino; Francesca Perut; Caterina Fotia; Sofia Avnet; Giacomo Sabbioni
Journal:  Musculoskelet Surg       Date:  2009-11-24

7.  Local Application of Isogenic Adipose-Derived Stem Cells Restores Bone Healing Capacity in a Type 2 Diabetes Model.

Authors:  Christoph Wallner; Stephanie Abraham; Johannes Maximilian Wagner; Kamran Harati; Britta Ismer; Lukas Kessler; Hannah Zöllner; Marcus Lehnhardt; Björn Behr
Journal:  Stem Cells Transl Med       Date:  2016-04-21       Impact factor: 6.940

8.  Is the expression of Transforming Growth Factor-Beta1 after fracture of long bones solely influenced by the healing process?

Authors:  Georg Kaiser; Anita Thomas; Julia Köttstorfer; Mathias Kecht; Kambiz Sarahrudi
Journal:  Int Orthop       Date:  2012-05-24       Impact factor: 3.075

9.  Reply to the letter to the editor: Bone marrow aspirate concentrate and platelet-rich plasma enhanced bone healing in distraction osteogenesis of the tibia.

Authors:  Dong Hoon Lee; Keun Jung Ryu; Jin Woo Kim; Kyung Chung Kang; Young Rak Choi
Journal:  Clin Orthop Relat Res       Date:  2014-04-30       Impact factor: 4.176

10.  Platelet-rich plasma for the treatment of lateral epicondylitis: sonographic assessment of tendon morphology and vascularity (pilot study).

Authors:  Salma Chaudhury; Mauricio de La Lama; Ronald S Adler; Lawrence V Gulotta; Brendan Skonieczki; Anthony Chang; Peter Moley; Frank Cordasco; Jo Hannafin; Stephen Fealy
Journal:  Skeletal Radiol       Date:  2012-09-22       Impact factor: 2.199
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