Literature DB >> 16365128

Allograft reconstruction for bone sarcoma of the tibia in the growing child.

L E Ramseier1, T I Malinin, H T Temple, W A Mnaymneh, G U Exner.   

Abstract

The outcome of tibial allograft reconstruction after resection of a tumour is inconsistent and has a high rate of failure. There are few reports on the use of tibial allografts in children with open growth plates. We performed 21 allograft reconstructions (16 osteoarticular, five intercalary) in 19 consecutive patients between seven and 17 years of age. Two had Ewing's sarcoma, one an adamantinoma and 16 osteosarcoma, one with multifocal disease. Five patients have died; the other 14 were free from disease at the time of follow-up. Six surviving patients (eight allograft reconstructions) continue to have good or excellent function at a mean of 59 months (14 to 132). One patient has poor function at 31 months. The other seven patients have a good or excellent function after additional procedures including exchange of the allograft and resurfacing or revision to an endoprosthesis at a mean of 101 months (43 to 198). The additional operations were performed at a mean of 47 months (20 to 84) after the first reconstruction. With the use of allograft reconstruction in growing children, joints and growth plates may be preserved, at least partially. Although our results remain inconsistent, tibial allograft reconstruction in selected patients may restore complete and durable function of the limb.

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Year:  2006        PMID: 16365128     DOI: 10.1302/0301-620X.88B1.16253

Source DB:  PubMed          Journal:  J Bone Joint Surg Br        ISSN: 0301-620X


  19 in total

1.  Similar survival but better function for patients after limb salvage versus amputation for distal tibia osteosarcoma.

Authors:  Andreas F Mavrogenis; Caterina Novella Abati; Carlo Romagnoli; Pietro Ruggieri
Journal:  Clin Orthop Relat Res       Date:  2012-01-24       Impact factor: 4.176

2.  Three-dimensional virtual bone bank system for selecting massive bone allograft in orthopaedic oncology.

Authors:  Zhigang Wu; Jun Fu; Zhen Wang; Xiangdong Li; Jing Li; Yanjun Pei; Guoxian Pei; Dan Li; Zheng Guo; Hongbin Fan
Journal:  Int Orthop       Date:  2015-03-15       Impact factor: 3.075

3.  Vascularized fibular medialization for reconstruction of the tibial defects following tumour excision.

Authors:  Abed El-Negery; Nabil Ahmed Elmoghazy; Mohamed Serry Abd-Ellatif; Adham Elgeidi
Journal:  Int Orthop       Date:  2017-04-19       Impact factor: 3.075

4.  Do Mesenchymal Stromal Cells Influence Microscopic Residual or Metastatic Osteosarcoma in a Murine Model?

Authors:  Megan E Aanstoos; Daniel P Regan; Ruth J Rose; Laura S Chubb; Nicole P Ehrhart
Journal:  Clin Orthop Relat Res       Date:  2016-03       Impact factor: 4.176

5.  Lower Limb Reconstruction Using Tibial Strut Autograft after Resection of Primary Malignant Bone Tumors in Skeletally Immature Patients.

Authors:  Bassem I Haddad; Mohammed S Alisi; Mohamad S Yasin; Mohammad Q Hamdan; Freih O Abu Hassan Frcs
Journal:  Arch Bone Jt Surg       Date:  2021-09

6.  Survival of massive allografts in segmental oncological bone defect reconstructions.

Authors:  P H J Bullens; N M Minderhoud; M C de Waal Malefijt; R P H Veth; P Buma; H W B Schreuder
Journal:  Int Orthop       Date:  2008-12-03       Impact factor: 3.075

7.  Allograft reconstruction after sarcoma resection in children younger than 10 years old.

Authors:  D Luis Muscolo; Miguel A Ayerza; Luis Aponte-Tinao; German Farfalli
Journal:  Clin Orthop Relat Res       Date:  2008-05-28       Impact factor: 4.176

8.  Role of Huntington procedure as a limb salvage surgery for complex gap nonunion of tibia in children.

Authors:  Abdul Qayyum Khan; Yasir Salam Siddiqui; Mazhar Abbas; Aamir Bin Sabir
Journal:  J Clin Orthop Trauma       Date:  2021-04-19

9.  Complications of limb salvage surgery in childhood tumors and recommended solutions.

Authors:  H Ozger; M Bulbul; L Eralp
Journal:  Strategies Trauma Limb Reconstr       Date:  2009-12-02

10.  Intercalary reconstructions with vascularised fibula and allograft after tumour resection in the lower limb.

Authors:  Katharina Rabitsch; Werner Maurer-Ertl; Ulrike Pirker-Frühauf; Christine Wibmer; Andreas Leithner
Journal:  Sarcoma       Date:  2013-05-23
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