Literature DB >> 16362769

Problems associated with biological markers of Alzheimer's disease.

H J Frey1, K M Mattila, M A Korolainen, T Pirttilä.   

Abstract

The etiopathogenesis of Alzheimer's disease (AD) is still unclear, although clinical diagnostic criteria exist and the neuropathology of AD has been studied in great detail during the last 20 years. The present study addresses certain problems in the search for biological markers for the diagnosis, as well as in the follow-up of the course of AD and its differential diagnosis and reports some of our own observations in comparison with other studies. These include protein, genetic and neuroimaging markers. The definitions of biological markers and search strategies are also discussed.

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Year:  2005        PMID: 16362769     DOI: 10.1007/s11064-005-8827-7

Source DB:  PubMed          Journal:  Neurochem Res        ISSN: 0364-3190            Impact factor:   3.996


  94 in total

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