| Literature DB >> 1636252 |
C A Angel1, R A Cullen, J H Pringle, I Lauder.
Abstract
The expression of vimentin in Reed-Sternberg cells in 61 samples of Hodgkin's disease (HD) was examined using an avidin-biotin-peroxidase complex technique. Forty biopsies (66%) expressed vimentin, and expression was seen in all subtypes of HD. No immunophenotypic differences between vimentin-positive and vimentin-negative cases were noted. The significance of such expression is unclear, but may be related to the alterations in growth and differentiation that are typical of neoplastic cells.Entities:
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Year: 1992 PMID： 1636252 DOI： 10.1007/bf01607132
Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histopathol ISSN： 0174-7398