BACKGROUND: To investigate the effect of ventilator-associated pneumonia (VAP) on the prognosis of head trauma patients. METHODS: We performed a retrospective case-control study in which 57 head trauma patients with VAP were matched to 57 head trauma patients without VAP. Matching criteria were age (+/-5 years), Glasgow Coma Scale score (+/-2), Injury Severity Score (+/-5), Simplified Acute Physiology Score II (+/-5), and duration of exposure to mechanical ventilation. RESULTS: The most causative organisms of VAP were Pseudomonas aeruginosa, and Acinetobactor baumannii (36.8% and 33.8% of isolated organisms, respectively). The duration of mechanical ventilation, intensive care unit stay, and hospital stay were significantly increased in case patients (13 +/- 8.4, 24.5 +/- 18, and 30.8 +/- 18.6 days, respectively) compared with control patients (8.3 +/- 4.3, 12.3 +/- 8, and 20.3 +/- 18.7 days, respectively). Mortality rate was also higher in case (29.8%) than in control (12.3%) patients (p = 0.02). CONCLUSION: We conclude that the occurrence of VAP caused by high-risk organisms in cranial trauma patients may increase the risk of death, the mechanical ventilation duration, the intensive care unit stay, and the hospital stay.
BACKGROUND: To investigate the effect of ventilator-associated pneumonia (VAP) on the prognosis of head traumapatients. METHODS: We performed a retrospective case-control study in which 57 head traumapatients with VAP were matched to 57 head traumapatients without VAP. Matching criteria were age (+/-5 years), Glasgow Coma Scale score (+/-2), Injury Severity Score (+/-5), Simplified Acute Physiology Score II (+/-5), and duration of exposure to mechanical ventilation. RESULTS: The most causative organisms of VAP were Pseudomonas aeruginosa, and Acinetobactor baumannii (36.8% and 33.8% of isolated organisms, respectively). The duration of mechanical ventilation, intensive care unit stay, and hospital stay were significantly increased in case patients (13 +/- 8.4, 24.5 +/- 18, and 30.8 +/- 18.6 days, respectively) compared with control patients (8.3 +/- 4.3, 12.3 +/- 8, and 20.3 +/- 18.7 days, respectively). Mortality rate was also higher in case (29.8%) than in control (12.3%) patients (p = 0.02). CONCLUSION: We conclude that the occurrence of VAP caused by high-risk organisms in cranial traumapatients may increase the risk of death, the mechanical ventilation duration, the intensive care unit stay, and the hospital stay.
Authors: Matthew Ryan Kesinger; Raj G Kumar; Amy K Wagner; Juan Carlos Puyana; Andrew P Peitzman; Timothy R Billiar; Jason L Sperry Journal: J Trauma Acute Care Surg Date: 2015-02 Impact factor: 3.313
Authors: Meghan M Cirulis; Mitchell T Hamele; Chris R Stockmann; Tellen D Bennett; Susan L Bratton Journal: Pediatr Crit Care Med Date: 2016-02 Impact factor: 3.624
Authors: C Michael Dunham; Anthony F Cutrona; Brian S Gruber; Javier E Calderon; Kenneth J Ransom; Laurie L Flowers Journal: Int J Burns Trauma Date: 2014-02-22